The Unique i-PDeA Analysis Method
What Is i-PDeA? – An Introduction Through Application Examples –
This new analysis method analyzers and detects unseparated peaks and small peaks concealed in the main component. It reduces the time required for considering separation conditions and plays a complementary role in quantitative analysis.
Here, we introduce some benefits of i-PDeA through application examples.
Example 1: I have developed an ultrafast analysis method, but want to further reduce analysis time. However, shortening the analysis time would affect separation.
・When you apply i-PDeA, you can selectively visualize only the components you want to view, even peaks that that are not separated!
Example 2: I want to correctly quantify the impurities that are eluted in the tailing of the main component peak.
・With i-PDeA, no additional consideration of separation conditions is required! Quantitative calculation can be done directly!
Compared to existing peak integration methods such as tailing (tangent skim method) and vertical separation (vertical skim method), i-PDeA permits quantitative calculation of impurities with higher precision!
Example 3: Separation of position isomer compounds fails to work well.
・Achieve separation using i-PDeA even though the spectral patterns are similar
Even though the difference in absorption wavelength between 1,2-dimethoxybenzene (274.2 nm wavelength) and 1,3-dimethoxybenzene (273.6 nm) is only 0.6 nm, the individual chromatograms can be obtained!