Automation and Efficiency Improvement Solutions (HPLC and LC-MS)

Multiple automation technologies (such as for dispensing liquids, centrifuging, and heating) can be used in combination based on the given analytical application, such as for automating pretreatment processes necessary for analyzing glycan modifications of antibodies. This will eliminate operating errors and pretreatment variability.

Functionality for automatically starting up the system, monitoring mobile phase reservoir levels, and self-diagnosing and restoring solvent delivery pumps can improve workflow efficiency and increase laboratory productivity.

Gradient conditions and various other parameter settings are automatically optimized to satisfy specified criteria (e.g., separation level), such as by switching between different mobile phases and columns.

Automatic dilution functionality included with the autosampler reduces the burden on analysts by automating sample dilution and calibration curve creation steps that previously required tedious pipetting operations.

Operator workloads can be reduced by using a flow vial autosampler to automatically acquire samples at fixed intervals and check them for trend changes over time during synthesis reaction monitoring or by automatically injecting them into the analytical instrument during formulation elution testing.

Functionality for automatically generating analysis schedules, used to help evaluate analysis scale parameter settings, and functionality for scaling up those settings once they are determined, helps ensure preparative chromatography can be performed with confidence, even by analysts without preparative experience.

Automation and Efficiency Improvement Solutions (HPLC and LC-MS)

Just as robots equipped with AI functionality are offering major changes to our lives, continuous advancements in Shimadzu HPLC, LC-MS, data analysis software, and pretreatment systems are significantly changing how day-to-day analytical operations are performed.