Achievements
  • Presentations at Conferences
  • Publication
2018.09

Simultaneous Analysis of 42 Chiral Amino Acids Produced by Intestinal Microbiota in Biological Samples by High-throughput LC-MS/MS

RSC (The Royal Society of Chemistry) Tokyo International Conference 2018, Chiba, Japan

  • Akihiro Kunisawa 1,2
  • Takanari Hattori 1,2
  • Shuichi Kawana 1
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 2
  • Mitsuharu Matsumoto 3
More details
  • 1 Shimadzu Corporation
  • 2 Graduate School of Engineering, Osaka University
  • 3 Kyodo Milk Industry Co. Ltd.
2018.07

Investigation of 42 Chiral Amino Acids Produced by Intestinal Microbiota in Biological Samples by High-throughput Comprehensive LC-MS/MS

HPLC 2018, Washington, U.S.

  • Akihiro Kunisawa 1,2
  • Takanari Hattori 1,2
  • Shuichi Kawana 2
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 2
  • Junko Iida 1,2
  • Eiichiro Fukusaki 1,3
  • Mitsuharu Matsumoto 4
More details
  • 1 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 2 Shimadzu Corporation, Kyoto
  • 3 Graduate School of Engineering, Osaka University
  • 4 Kyodo Milk Industry Co. Ltd.
2018.07

Comprehensive Analyses of fecal metabolites in mice using GC-MS/MS and LC-MS/MS

The 45th Biological Mass Spectrometry Conference, Miyagi, Japan

  • Takanari Hattori 1,2
  • Akihiro Kunisawa 1,2
  • Shuichi Kawana 1
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 2,3
  • Mitsuharu Matsumoto 4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Engineering, Osaka University
  • 4 Kyodo Milk Industry Co.,Ltd.
2018.06

Trial for Food Quality Evaluation with Machine Learning Schemes

Metabolomics Conference 2018, Seattle, U.S.

  • Takero Sakai 1
  • Yoshihiro Aoyama 1
  • Kiyomi Arakawa 1
More details
  • 1 Shimadzu Corporation
2018.06

Determination of 42 chiral amino acids in biological samples using high-throughput and comprehensive LC-MS/MS: Investigation of D-amino acids produced by intestinal microbiota

Metabolomics Conference 2018, Seattle, U.S.

  • Takanari Hattori 1,2
  • Akihiro Kunisawa 1,2
  • Shuichi Kawana 1
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 2,3
  • Mitsuharu Matsumoto 4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Engineering, Osaka University
  • 4 Kyodo Milk Industry Co. Ltd.
2018.06

Automated visualization of multiomics (metabolomics, proteomics, fluxomics and transcriptomics) data on Garuda, a connectivity platform for biological analytics

ASMS 2018, San Diego, U.S.

  • Shinji Kanazawa 1,2,3
  • Yohei Yamada 1
  • Hiroyuki Yasuda 1
  • Fumio Matsuda 3
  • Samik Ghosh 4
  • Takeshi Hase 4
  • Nikolaos Tsorman 4
  • Yukiko Matsuoka 4
  • Shigeki Kajihara 1
  • Hiroaki Kitano 4
  • Eiichiro Fukusaki 5
  • Junko Iida 1,2
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Information Science and Technology
  • 4 The Systems Biology Institute
  • 5 Graduate School of Engineering, Osaka University
2018.05

Analyses of fecal metabolites in mice using LC-MS/MS - Efficient data analysis and visualization

Mass Spectrometry and Proteomics 2018, Osaka, Japan

  • Takanari Hattori 1,2
  • Akihiro Kunisawa 1,2
  • Shuichi Kawana 1
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 2,3
  • Mitsuharu Matsumoto 4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Engineering, Osaka University
  • 4 Kyodo Milk Industry Co.,Ltd.
2018.02

High-throughput comprehensive LC-MS/MS analysis of trace D- and L- amino acids using extra-facile chiral separation and column switching system

PITTCON 2018, Orland, U.S.

  • Akihiro Kunisawa 1,2
  • Yuki Uno 1
  • Shinichi Kawano 1,2
  • Junko Iida 1,2
  • Yosuke Nakano 3
  • Eiichiro Fukusaki 2,3
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Engineering, Osaka University
2018.01

Automatic visualization of multi-omics data using Garuda Platform - Application to Calvin cycle

Symposium of The Division of Innovative Research for Drug Development, Osaka, Japan

  • Yuji Kanazawa 1
  • Yohei Yamada 1
  • Hitoyuki Yasuda 1
  • Fumio Matsuda 3
  • Samik Ghosh 2
  • Takeshi Hase 2
  • Nikolaos Tsorman 2
  • Yukiko Matsuoka 2
  • Shigeki Kajiwara 1
  • Eichiro Fukusaki 3
  • Junko Iida 1,3
More details
  • 1 Shimadzu Corporation
  • 2 The Systems Biology Institute
  • 3 Osaka University
2017.11

Automatic Visualization Pipeline of Multi-Omics Data on Garuda Platform: Application of Transcriptome Data

11th Metabolome Symposium

  • Yohei Yamada 1
  • Shinji Kanazawa 1
  • Hiroyuki Yasuda 1
  • Fumio Matsuda 3
  • Samic Ghosh 2
  • Takeshi Hase 2
  • Nikolaos Tsorman 2
  • Yukiko Matsuoka 2
  • Shigeki Kajihara 1
  • Hiroaki Kitano 2
  • Eiichiro Fukusaki 3
  • Junko Iida 1,3
More details
  • 1 Shimadzu Corporation
  • 2 The Systems Biology Institute
  • 3 Osaka University
2017.11

Automatic Chromatographic Peak Picking using Deep Learning for a number of chromatograms (2): algorithm development

11th Metabolome Symposium

  • Shinji Kanazawa 1
  • Akihiro Kunisawa 1
  • Hidetoshi Terada 1
  • Hiroyuki Yasuda 1
  • Yohei Yamada 1
  • Shigeki Kajihara 1
  • Norio Mukai 1
  • Junko Iida 1
  • Takeshi Osoekawa 2
  • Yusuke Hida 2
  • Yuji Kanazawa 2
  • Yuzuru Yamakage 3
More details
  • 1 Shimadzu Corporation
  • 2 Fujitsu Laboratories Ltd.
  • 3 Fujitsu Ltd.
2017.11

Automatic Chromatographic Peak Picking using Deep Learning for a number of chromatograms (1): algorithm development

11th Metabolome Symposium

  • Takeshi Osoekawa 1
  • Yusuke Hida 1
  • Yuji Kanazawa 1
  • Yuzuru Yamakage 2
  • Shinji Kanazawa 3
  • Akihiro Kunisawa 3
  • Hidetoshi Terada 3
  • Hiroyuki Yasuda 3
  • Yohei Yamada 3
  • Shigeki Kajihara 3
  • Norio Mukai 3
  • Junko Iida 3
More details
  • 1 Fujitsu Laboratories Ltd.
  • 2 Fujitsu Ltd.
  • 3 Shimadzu Corporation
2017.9

Measurement of Metabolites in Mice Feces by LC-MS/MS: Comparison between Young Mice and Old Mice

The 69th Annual Meeting of the Society for Biotechnology, Japan

  • Akihiro Kunisawa 1,2
  • Takanari Hattori 1,2
  • Yukari Oka 1
  • Shuichi Kawana 1
  • Shinichi Kawano 1,2
  • Yoshihiro Hayakawa 1
  • Junko Iida 1,2
  • Eiichiro Fukusaki 3
  • Mitsuharu Matsumoto 4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Graduate School of Engineering, Osaka University
  • 4 Kyodo Milk Industry Co. Ltd.
2017.9

High-throughput comprehensive LC-MS/MS analysis of trace D- and L- amino acids using extra-facile chiral separation and column switching

RSC Tokyo International Conference 2017

  • Akihiro Kunisawa 1,2
  • Yuki Uno 1
  • Shinichi Kawano 1,2
  • Junko Iida 1,2
  • Yosuke Nakano 3
  • Eiichiro Fukusaki 2,3
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Osaka University
2017.7

Automated Visualization of Metabolome, Proteome and Fluxome Data on Garuda - a Connectivity Platform for Biomedical Analytics

The 44th Biological Mass Spectrometry Conference

  • Fumio Matsuda 1
  • Yohei Yamada 2
  • Samik Ghosh 3
  • Takeshi Hase 3
  • Syohei Kinoshita 1
  • Shunsuke Nishino 1
  • Atsumi Tomita 1
  • Nikolaos Tsorman 3
  • Atsuhiko Toyama 2
  • Shigeki Kajihara 2
  • Norio Mukai 2
  • Yukiko Matsuoka 3
  • Hiroshi Shimizu 1
  • Eiichiro Fukusaki 4,5
  • Hiroaki Kitano 3
  • Junko Iida 2,5
More details
  • 1 School of Information Science and Technology, Osaka University
  • 2 Shimadzu Corporation
  • 3 The Systems Biology Institute
  • 4 Graduate School of Engineering, Osaka University
  • 5 Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
2017.6

Automated Visualization of Metabolome, Proteome and Fluxome Data on Garuda - a Connectivity Platform for Biomedical Analytics

ASMS2017

  • Fumio Matsuda 1
  • Yohei Yamada 2
  • Samik Ghosh 3
  • Takeshi Hase 3
  • Syohei Kinoshita 1
  • Shunsuke Nishino 1
  • Atsumi Tomita 1
  • Nikolaos Tsorman 3
  • Atsuhiko Toyama 2
  • Shigeki Kajihara 2
  • Norio Mukai 2
  • Yukiko Matsuoka 3
  • Hiroshi Shimizu 1
  • Eiichiro Fukusaki 4,5
  • Hiroaki Kitano 3
  • Junko Iida 2,5
More details
  • 1 School of Information Science and Technology, Osaka University
  • 2 Shimadzu Corporation
  • 3 The Systems Biology Institute
  • 4 Graduate School of Engineering, Osaka University
  • 5 Osaka University Shimadzu Analytical Innovation Research Laboratory, Graduate School of Engineering, Osaka University
2017.6

Mice fecal metabolomics by LC-MS/MS: Comparison between young mice and old mice

ASMS2017

  • Takanari Hattori 1,2
  • Shuichi Kawana 1
  • Yoshihiro Hayakawa 1
  • Eiichiro Fukusaki 3
  • Mitsuharu Matsumoto 4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University Shimadzu Analytical Innovation Research Laboratory
  • 3 Osaka University
  • 4 Kyodo Milk Industry Co. Ltd.
2017.5

Automatic visualization of trans-omics data of mass spectrometry using Garuda connectivity platform

65th Annual Conference on Mass Spectrometry, Japan

  • Yohei Yamada 1
  • Fumio Matsuda 2
  • Samik Ghosh 3
  • Takeshi Hase 3
  • Syohei Kinoshita 2
  • Shunsuke Nishino 2
  • Atsumi Tomita 2
  • Nikolaos Tsorman 3
  • Atsuhiko Toyama 1
  • Shigeki Kajihara 1
  • Norio Mukai 1
  • Yukiko Matsuoka 3
  • Hiroshi Shimizu 2
  • Eiichiro Fukusaki 2,4
  • Hiroaki Kitano 3
  • Junko Iida 1,4
More details
  • 1 Shimadzu Corporation
  • 2 Osaka University
  • 3 The Systems Biology Institute
  • 4 Osaka University Shimadzu Analytical Innovation Research Laboratory
2017.5

Investigation of Chiral Amino Acids Analysis using Column Switching System

65th Annual Conference on Mass Spectrometry, Japan

  • Toshikazu Minohata 1
  • Yuki Uno 1
  • Jun Watanabe 1
  • Hidetoshi Terada 1
  • Junko Iida 1
  • Yosuke Nakano 2
  • Eiichiro Fukusaki 2
More details
  • 1 Shimadzu Corporation
  • 2 Graduate School of Engineering, Osaka University
2016.10

Analyses of fecal metabolites in mice using LC and LC-MS/MS

10th Metabolome Symposium

  • Takanari Hattori 1,2
  • Yukari Oka 1
  • Shuichi Kawana 1
  • Mitsuharu Matsumoto 3
  • Yoshihiro Hayakawa 1
More details
  • 1 Shimadzu Corporation
  • 2 Graduate School of Engineering, Osaka University
  • 3 Kyodo Milk Industry Co.,Ltd. Research Laboratories
2016.6

13C-metabolic flux analysis of microbes by using novel fragmentations of tert-butyldimethylsilyl (tBDMS)-amino acid derivatives with GC-MS/MS.

ASMS (American Society for Mass Spectrometry) 64th conference on mass spectrometry and allied topics (June 5-9, 2016 in San Antonio, USA)

  • Nobuyuki Okahashi 1
  • Shuichi Kawana 2
  • Junko Iida 2
  • Hiroshi Shimizu 1
  • Fumio Matsuda 1
More details
  • 1 Graduate School of Information Science and Technology, Osaka University
  • 2 Shimadzu Co.
2016.5

Investigations of novel amino acids fragment ions using GC-MS/MS for precise 13C-metabolic flux analysis

MSSJ (the Mass Spectrometry Society of Japan) 64th Annual Conference on Mass Spectrometry (May 18-20, 2016, in Osaka, Japan)

  • Nobuyuki Okahashi 1
  • Shuichi Kawana 2
  • Junko Iida 2,3
  • Hiroshi Shimizu 1
  • Fumio Matsuda 1
More details
  • 1 Graduate School of Information Science and Technology, Osaka University
  • 2 Shimadzu Corporation
  • 3 Graduate School of Engineering, Osaka University
2016.3

Improvement of the 13C-metabolic flux analysis using gas chromatography-tandem quadrupole mass spectrometry.

SCEJ(the Society of Chemical Engineers, Japan) 81st Annual Meeting (March 13-15, in Osaka, Japan)

  • *Okahashi Nobuyuki 1
  • Kawana Shuichi 2
  • Matsuda Fumio 1
  • Iida Junko 2
  • Shimizu Hiroshi 1
More details
  • 1 Osaka U.
  • 2 Shimadzu
2015.10

Osaka University - Shimadzu Workshop
Frontier in Biotechnology -from Metabolites to Regenerative Cells

Pathumwan Princess Hotel, Bangkok, 9th October 2015

More details

Agenda

  1. 1. Cutting-edge biotechnology from Osaka University and collaboration with Shimadzu
      └ The Presentation file - Contributing through Science and Technology - Collaboration Between Osaka University and Shimadzu (PDF 3,807 kB)
      └ The Presentation file - Mass Spectrometry - A Powerful tool for metabolomics (PDF 7,060 kB)
  2. 2. Cutting-edge biotechnology from Thailand - Metabolomics and metabolomics profiling with food
  3. 3. Cutting-edge biotechnology and pioneers of biotechnology - Osaka University
  4. 4. Cutting-edge biotechnology from Thailand - Pharmaceutical, healthcare and agricultural applications

The brochure of the program details and the invitation notes (PDF 1,186 kB)

The speakers were from

Osaka University
(1) Division of Advanced Science and Biotechnology, Graduate School of Engineering, Osaka University,(2) Osaka University, International Center for Biotechnology (ICBiotech),(3) Osaka University and Shimadzu Analytical Innovation Research Laboratory
Thailand
(1)Chulalongkorn University, (2) Kasetsart University,(3) King Mongkut's University of Technology Thonburi(KMUTT),(4) Mahidol University,(5) National Center for Genetic Engineering and Biotechnology (BIOTEC)
Shimadzu Group
(1) Shimadzu Corporation (Japan),(2) Shimadzu (Asia Pacific) Pte. Ltd. (Singapore),(3) Bara Scientific Co. Ltd. (The one of Shimadzu's distributors in Thailand)
2015.7

Fully automated on-line sample extraction and analysis of residual pesticides in agricultural products by using on-line SFE-SFC-MS

SFC 2015, 9th International Conference on Packed-Column SFC

  • Takanari Hattori 1
  • Takato Uchikata 1
  • Hidetoshi Terada 1
  • Chigusa Ichikawa 1
  • Yasuhiro Funada 1
  • Yayoi Ichiki 2
  • Miho Sakai 3
  • Takashi Ando 3
  • Yoshihiro Izumi 4, 5
  • Eiichiro Fukusaki 5
  • Takeshi Bamba 4, 5
More details
  • 1 Shimadzu Corporation, Kyoto, Japan
  • 2 Miyazaki Enterprise Promotion Organization, Miyazaki, Japan
  • 3 Miyazaki Agricultural Research Institute, Miyazaki, Japan
  • 4 Kushu University, Fukuoka, Japan
  • 5 Osaka University, Suita, Japan
2015.6

Fully automated on-line sample extraction and analysis of residual pesticides in agricultural products by using on-line SFE-SFC-MS

63rd ASMS Conference on Mass Spectrometry and Allied Topics

  • Takanari Hattori 1
  • Takato Uchikata 1
  • Hidetoshi Terada 1
  • Chigusa Ichikawa 1
  • Yasuhiro Funada 1
  • Yayoi Ichiki 2
  • Miho Sakai 3
  • Takashi Ando 3
  • Yoshihiro Izumi 4, 5
  • Eiichiro Fukusaki 5
  • Takeshi Bamba 4, 5
More details
  • 1 Shimadzu Corporation, Kyoto, Japan
  • 2 Miyazaki Enterprise Promotion Organization, Miyazaki, Japan
  • 3 Miyazaki Agricultural Research Institute, Miyazaki, Japan
  • 4 Kushu University, Fukuoka, Japan
  • 5 Osaka University, Suita, Japan
2015.3

Comparison of metabolite maker discovery in a yeast between GC-MS and GC-MS/MS

The 2015 Annual Conference of the Japan Society for Bioscience, Biotechnology and Agrochemistry (28 March 2015 Okayama, Japan)

  • Takero Sakai 1
  • Shuichi Kawana 1
  • Junko Iida 1
  • Takeshi Bamba 2
  • Eiichiro Fukusaki 2
More details
  • 1 Shimadzu Co.,
  • 2 Dept. Biotech., Grad. Sch. Eng., Osaka Univ.,
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