Analysis of PFAS Specified in EPA Method 537 and Beyond using Shimadzu UFMS™

Introduction

This application news demonstrates the use, performance and compatibility of Shimadzu Ultra-fast Mass Spectrometry (UFMS^TM) for EPA Method 537 with an expanded compound panel of seven additional PFAS. A total of 27 PFAS compounds were extracted, separated and detected with triple quadrupole mass spectrometers, LCMS-8045 and LCMS-8050. Recoveries of 86–106% (LCMS-8050) and 77–104% (LCMS-8045) were well within the limits outlined in EPA 537. Method detection limits of 0.7–1.7 ng/L (ppt) (LCMS-8050) and 0.7–3.3 ng/L (LCMS-8045) were obtained and both systems fulfilled all of the EPA’s requirements for PFAS analysis in drinking water. Keywords: Per- and Polyfluorinated Alkyl Substances, PFAS, Perfluorinated Compounds, PFCs, Drinking Water, PFOA, PFOS, Persistent Organic Pollutants, POPs

June 2, 2022 GMT