Analysis of 28 Common PFAS Compounds using the Compact Single Quadrupole LCMS-2050

User Benefits

- Can quantitatively acquire LCMS data of individual PFAS compounds with a straightforward workflow. - Sensitive analysis of PFAS targets detected down to 0.5 ng/mL. - Fast and accurate separation with a compact, single quadrupole detector — the Shimadzu LCMS-2050. - Simultaneous analysis in SIM and scan modes allows monitoring of suspected degradation or transformation products.

Introduction

The growing concern of per- and polyfluoroalkyl substances (PFAS) in the environment has driven the need for quick, inexpensive measurement of PFAS for evaluating PFAS removal by novel treatment technologies, monitoring of remediation projects, or added capability to detect emerging contaminants. Most PFAS applications require the sensitivity and specificity of the triple quadrupole mass spectrometer; however, this presents significantly higher maintenance costs in a much larger laboratory footprint. The compact, affordable LCMS-2050 single quadrupole mass spectrometer can be easily integrated into existing laboratories for measurement of PFAS in diverse samples where adherence to regulated methods (e.g., EPA 533, 537.1, and 1633) is not required, or samples where expected concentrations are larger than sub ppb levels.

July 28, 2025 GMT