Separation of Styrene Oligomers Using Recycle Fractionation System

User Benefits

- Recycle fractionation enables high-purity prep purification of compounds that are difficult to separate. - GPC analysis and recycle fractionation can be performed within a single HPLC setup. - Automated recycle fractionation using the time program function originally equipped in LabSolutions and batch analysis function.

Introduction

Prep LC is widely used across pharmaceutical, food, and chemical industries for purifying target compounds from mixtures, identifying active ingredients in natural products, and structural analysis of impurities and unknown compounds. It is important to separate target compounds from co-existing compounds for the collection with high purity. However, it is difficult in some cases to separate target compounds due to limitations of optimizing separation conditions such as column selection. This article introduces the principles and workflow of prep purification using the recycle separation method—a technique for improving separation—using the example separation of styrene oligomers.

November 18, 2025 GMT