Pfizer drives cancer research breakthroughs with supercritical fluid chromatography

Supercritical fluid chromatography (SFC) is a separation technique that uses a supercritical fluid (most commonly carbon dioxide) as the mobile phase to efficiently purify compounds, offering faster processing, lower solvent consumption, and a more environmentally friendly alternative to traditional liquid chromatography (LC) methods. In this interview, Jeff Elleraas, Principal Scientist at Pfizer’s Global Research and Development in La Jolla, California, shares insights into the role of SFC and how machine learning and AI are transforming chiral separations. Plus, discover Pfizer’s mission to tackle the toughest challenges in oncology research, accelerate medicinal chemistry innovations, and create greener, more efficient processes for developing novel cancer treatments.