Very fast separation speed due to the relatively low viscosity of supercritical fluid...
Nexera UC
Supercritical Fluid Extraction / Supercritical Fluid Chromatograph
- Overview
- Features
- Applications
- Specs
- Downloads
- Configuration
- Columns
- Consumables
- Options
- Case Studies
- Support
Supercritical Fluid Extraction/Chromatograph System
Conventional LC/MS and GC/MS face these challenges.

Time-consuming sample preparation
Degradation of labile compounds during sample preparation
Low abundant peaks hidden in noise
Nexera UC provides uncompromising solutions.
Fully automated on-line sample preparation and analysis
Even labile compounds can be analyzed without degradation
Unified speed of analysis, sensitivity, and resolution
Just another chromatographic technique... or the only technique you'll need?

Nexera UC improves your analytical workflow by utilizing a completely new separation technology, Unified Chromatography, which unites sample preparation, analysis with various separation modes, and high-sensitivity detection.
Comparison of QuEChERS sample preparation and Nexera UC in the analysis of residual pesticides
A typical sample preparation takes 35 minutes and requires several manual steps. With Nexera UC, the same sample can be ready for on-line SFE/SFC analysis in as little as five minutes with only a few simple sample preparation steps.

* "Miyazaki Hydro-Protect", Patented in Japan No.3645552
Hundreds of compounds are simultaneously analyzed with Nexera UC. These include pesticides that are usually analyzed with LC and LC/MS/MS or GC and GC/MS/MS. Nexera UC enables analysis of compounds over a wide polarity range.

Analysis of Compounds with Wide Polarity Range
Awards
2015 R&D magazine Award

The award from R&D magazine recognizes Shimadzu’s Nexera UC system as one of the 100 most technically significant new products of the year in the analytical and testing category.
R&D Magazine chose the Nexera UC system because its fully automated technology opens up new analytical opportunities in many fields, including food products, drug discovery and delivery, chemicals, pharmaceuticals, and cleaning validation.
With industry-leading throughput and superior levels of sensitivity, the system eliminates the need for complicated sample pre-treatment and reduces the possibility of human error during analysis.
more detail
Pittcon Editors' Gold Award 2015
The Pittcon Editors' Awards recognize the most innovative products presented at Pittcon for the first time based on votes by the media corps.
Editors awarded the Nexera UC for its ability to provide a workflow solution that addresses the bottleneck in real-world sample analyses.

Features
-
Solutions provided by Nexera UC
Very fast separation speed due to the relatively low viscosity of supercritical fluid... -
Improved separation and detection capabilities result from the low viscosity and high diffusion coefficient of...
-
Supercritical fluid has unique properties different from liquid.
Using SFC in front of a mass spectrometer offers... -
Low dead volume back pressure regulator suppresses diffusion of peaks and can transfer the total eluate directly to an mass spectrometer to...
Movies
-
Nexera UC Supercritical Fluid Extraction/Chromatograph System Narration Eddition
News / Events
-
Don’t miss out! Join our latest webinar collaborated with SelectScience on June 28, 2022.
“Dual deconvolution of LC-PDA-MS data: A fast-track approach for chemical composition and impurity analysis”
-
Shimadzu has released the LCMS-2050 High-Performance Liquid Chromatograph Mass Spectrometer.
The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy to use high-level performance and compactness.
-
LabSolutions CS has been upgraded to Ver. 6.115.
LabSolutions CS features an innovative operating environment and provides complete data management to ensure secure information in networked laboratories.
-
Shimadzu has released the CoreFocus Library.
CoreFocus Library is a digital library where you can find and learn different methods for analyzing your target compounds.
-
Shimadzu has released the Nexera XS inert.
The Nexera XS inert system offers the ideal solution for the separation of biomolecules by combining the elevated pressure tolerance of a UHPLC system with complete inertness of the sample flow path, ensured by the absence of wetted metal surfaces and offering ultra-high resistance to corrosion.
-
Shimadzu has released Method Development System
LabSolutions MD uses an “Analytical Quality by Design” (AQbD) approach for achieving efficient method development by designing analysis methods based on science and risk. All workflow steps can be completed using LabSolutions MD, including analyzing samples using the experimental design, building a design space by using the analytical results, and evaluating robustness after deciding the optimal analytical conditions.
Sustainability initiatives
- Overview
- Features
- Applications
- Specs
- Downloads
- Configuration
- Columns
- Consumables
- Options
- Case Studies
- Support