The analysis time can be effectively shortened because an excellent chromatographic resolution can be maintained even at higher flow rates than those typically used for HPLC.
Nexera UC
Supercritical Fluid Extraction / Supercritical Fluid Chromatograph
Supercritical Fluid Extraction/Chromatograph System
Preparative scale Nexera™ UC Prep is Here
Advances in column technology have led to a renewed interest in supercritical fluid chromatography (SFC), which uses a supercritical fluid as mobile phase. Compared to liquid, supercritical fluids have low viscosity and high diffusivity. By combining SFC with Supercritical fluid extraction (SFE), which utilizes the high permeability and diffusivity of supercritical fluids, the extraction and analysis of target components from solid samples can be automated. The new analytical technology “Unified Chromatography” improves the analytical workflow by integrating sample extraction, analysis by various separation modes, and high-sensitivity detection.
Features
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Separation results can be quickly obtained during method development by screening with both SFC and UHPLC. -
By using a fraction collector, small-volume fractionation is also possible (ex:1.5 mL vials). -
Target compounds are extracted from solid samples, and then automatically transferred to SFC. -
By using SFC, the consumption of organic solvent is reduced by 94.2%, compared to the normal-phase.
Movies
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Overview of the analytical technologies using supercritical fluid
Green Analytical Chemistry (GAC) is a concept of designing analytical methods that are friendly to both chemists and environment. It is necessary for the GAC-based methods to retain the same analytical performance (e.g., accuracy, sensitivity) as those by their conventional counterparts. Large solvent consumption is particularly concerning in a food analysis where complicated sample extraction and chromatography are routinely practiced. Supercritical fluid is a state of matter just like gas or liquid, and the characteristics of CO2 supercritical fluid are nonflammability, easy handling, and low toxicity, which are relevant to the operator safety. This webinar will show the characteristics of supercritical fluids CO2, the practicality of analytical techniques using it, and the applicability to GAC.
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Nexera UC Supercritical Fluid Extraction/Chromatograph System Narration Eddition
News / Events
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Determination of heterocyclic oxygen compounds in Citrus essential oils by Supercritical fluid chromatography-tandem mass spectrometry
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New Nexera UC Prep Semi-Preparative Supercritical Fluid Chromatography System
Semi-Preparative Supercritical Fluid Chromatography System
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New Nexera UC Supercritical Fluid Extraction / Supercritical Fluid Chromatograph
Nexera UC improves your analytical workflow by utilizing a completely new separation technology, Unified Chromatography, which unites sample separation, analysis with various separation modes, and high-sensitivity detection.
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New Nexera Prep Preparative Purification Liquid Chromatograph
The Nexera Prep Purification System provides optimal solutions for your laboratory needs.
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Shimadzu has released the Shim-pack™ SUR-Na Columns for Ligand Exchange Chromatography.
Shim-pack™ SUR-Na, a ligand exchange chromatography column, offers excellent performance by combining size exclusion mode and sodium-based ligand exchange mode to provide superior separation of sugar components. Pure water can be used for the mobile phase, resulting in less effort to prepare for the analysis.
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Efficient Method Development by automated pH Screening with LabSolutions MD
This article describes an example of using LabSolutions MD, a dedicated software for supporting method development, to automate pH screening by varying the mobile phase pH from 2.5 to 8.5 to evaluate the optimal pH level for separating 12 small-molecule drugs.
Awards
Sustainability initiatives
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3 Good health and well-being