Nexera UC Prep

Semi-Preparative Supercritical Fluid Chromatography System

Unparalleled performance, unparalleled flexibility

The Nexera™ UC Prep is a new preparative supercritical fluid chromatography (SFC) system that offers both the high basic performance developed for the previous Nexera UC model and original state-of-the-art preparative SFC technologies. It resolves a number of issues in preparative tasks, reducing labor and improving efficiency while fitting into pre-existing workflows. Not only does the Nexera UC Prep achieve superior recovery rates for purification, it provides flexible system configurations in a compact design, requiring low installation space and allowing you to maximize lab resources.

Rewriting the Book on Supercritical Fluid Chromatography

Supercritical carbon dioxide (CO₂) displays the qualities of both a liquid and a gas, making it the ideal choice of mobile phase in supercritical fluid chromatography (SFC). Historically, SFC has been overshadowed by other forms of chromatography such as high-performance liquid chromatography and gas chromatography. However, recent developments in SFC technology have transformed it into a highly accurate, sensitive and cost-effective solution that can outperform other chromatography. With the ability to analyze a range of polar and non-polar molecules, and easily transferable expertise and equipment, it's time to rethink SFC, and discover the advantages of supercritical CO₂.

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Features

Unique technology achieves higher recovery rates

-SFC shortens analysis times
-High recovery rates
-Stacked injection function eliminates waiting time
-Simple post-run processing
Solid autosamplers for increasing loading capacity

By using SFE, broadening of peak shape at loading a large volume is suppressed.
Prep Solutions enables a seamless preparative workflow

By using SFE, broadening of peak shape at loading a large volume is suppressed.
Compact, benchtop design

-Benchtop system that can be installed anywhere
-Wide range of flow rates available
$Fully automated on-line extraction and fractionation$

Fully automated on-line extraction and fractionation

Target compounds are extracted from solid samples, and then automatically transferred to SFC.
Nexera UC reduces environmental impact

By using SFC, the consumption of organic solvent is reduced by 94.2%, compared with the normal-phase HPLC.

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Latest Webinar

2022-03-03

LC Purification Series Session 3 - Semi-Preparative Scale LC Purification-

Liquid Chromatography

HPLC/UHPLC/SFC Systems

Preparative HPLC Systems

1. Principles, common issues and tips and tricks of semi-preparative chromatography 2. UFPLC-Ultra fast preparative and purification LC 3. Semi-preparative SFC scale purification

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Videos

Overview of the analytical technologies using supercritical fluid

Liquid Chromatography

Green Analytical Chemistry (GAC) is a concept of designing analytical methods that are friendly to both chemists and environment. It is necessary for the GAC-based methods to retain the same analytical performance (e.g., accuracy, sensitivity) as those by their conventional counterparts. Large solvent consumption is particularly concerning in a food analysis where complicated sample extraction and chromatography are routinely practiced. Supercritical fluid is a state of matter just like gas or liquid, and the characteristics of CO2 supercritical fluid are nonflammability, easy handling, and low toxicity, which are relevant to the operator safety. This webinar will show the characteristics of supercritical fluids CO2, the practicality of analytical techniques using it, and the applicability to GAC.
Nexera UC+FRC-40SF_2ｍLvial (side)

Liquid Chromatography

Direct fractionation into vials
Nexera UC+FRC-40SF_96well (up)

Liquid Chromatography

Direct fractionation into 96-well plate

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News / Events

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Awards

Pittcon Editors’ Gold Award 2019

Sustainability initiatives

2 Zero hunger
3 Good health and well-being
7 Affordable and clean energy
13 Climate action
14 Life Below Water
15 Life on land