Direct Analysis of Glyphosate, Glufosinate and AMPA in Beverages Using a Triple Quadrupole LC/MS/MS
Glyphosate and glufosinate are active ingredients in widely used foliar herbisides. When degraded in soil and water, glyphosate produces aminomethylphosphonic acid (AMPA) as a metabolite. Glyphosate, glufosinate and AMPA are all highly polar compounds, making retention in the reversed-phase mode with HPLC or LC-MS difficult. Therefore, analysis usually employs derivatization using FMOC. This article introduces a method for a high-sensitivity measurement of glyphosate, glufosinate and AMPA that does not require complex pretreatment or time-consuming derivatization. Featuring very simple pretreatment procedures comprising only filtering and dilution, the method obtained favorable recovery factors with actual samples.
- Content Type:
- Application
- Document Number:
- LAAN-A-LM-E151
- Product Type:
- Liquid Chromatograph-Mass Spectrometry, Mass Spectrometry
- Keywords:
- FMOC, FMOC-Cl, 9-Fluorenylmethyl chloroformate, Chloroformic acid 9-fluorenylmethyl ester, Derivatization, Residual pesticide, Food and Beverages, Food development, LCMS-8050
- Language:
- English
- File Name:
- jpo119002.pdf
- File Size:
- 73kb