Simple analysis of sialic acid linkage isomer

The linkage types of sialic acid can be determined from MS1 analysis by using SialoCapper-ID Kit. This eliminates the need for separation by LC, preparation of glycan standards, and MS/MS analysis. This kit enables highly reliable measurement data acquisition and labor-saving experiments.

Simple analysis of sialic acid linkage isomer

Improving sialoglycan sensitivity

SialoCapper-ID Kit improves sialoglycan sensitivity while stabilizing sialic acids and reducing their degradation. It also makes it easier to measure trace samples such as biological samples.
The mass spectrum becomes simpler and glycan analysis becomes easier.

Improving sialoglycan sensitivity

Versatility and scalability

SialoCapper-ID Kit can be used in combination with previous experimental procedures. Liquid-phase reaction is effective for both labeled and non-labeled glycans. In the solid-phase reaction used in combination with glycan binding beads such as BlotGlyco®, glycan purification and sialic acid derivatization can be achieved simultaneously.

Versatility and scalability

Supporting Tool for SialoCapper-ID Kit

The Supporting Tool for SialoCapper-ID Kit can estimate glycan composition from given m/z values in the results of mass spectrometry and deal with the mass change of sialic acid residues by sialic acid derivatization such as SALSA method.

 

Supporting Tool for SialoCapper-ID Kit

 

Recommended specifications for computers
-Operating system: Windows® 10 Pro 64 bit (Japanese/English)
-Memory: More than 8 GB
-Storage: More than 256 GB
-Optical drive: DVD drive

*A computer is not included for installing the software.

 

SialoCapper is a trademark of Shimadzu Corporation.
BlotGlyco is a registered trademark of Sumitomo Bakelite Co., Ltd.
Windows is either a registered trademark or a trademark of Microsoft Corporation in the United States and/or other countries.

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