SialoCapper-ID Kit

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SialoCapper-ID Kit

SialoCapper™-ID Kit reliably stabilizes sialic acid residues, enabling linkage isomer discrimination.

Our technology prevents the decomposition of sialic acid residues and ionization suppression. Furthermore, makes it possible to discriminate the linkage isomers of sialic acids by mass spectrometry.

Principle of MALDI-TOFMS 

 


Sialic Acid Linkage-Specic Alkylamidation (SALSA method)

Reaction scheme of SALSA method
Various types of mass spectrometers

Various types of mass spectrometers can be used for measuring glycans derivatized with the SialoCapper-ID Kit

 

The SALSA method involved in the SialoCapper-ID Kit was developed by Shimadzu corporation and improved in cooperation with Prof. Jun-Ichi Furukawa and Dr. Hisatoshi Hanamatsu at Hokkaido University.

 

 

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