Particle Size Analyzers Comparison

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Particle Size Analyzers Comparison

This page provides a quick overview of 4 models of Particle Size Analyzers. Choose the model that best suits your analysis needs from our laser diffraction particle size analyzer, nano particle size analyzer to dynamic particle image analysis system. ​

Contents

1. Summary of Product Features​

 

iSpect DIA-10

iSpect DIA-10 ​​

Reliable Particle Detection System
• Efficient Image Acquisition​​

Unprecedented Functionality and Performance
• Trace Sample Measurement
​• Small Dead Volume

Three-step Easy Measurement
• Autofocus Function for Easy Operation

 

SALD-7500nano

SALD-2300​​
SALD-7500nano ​​​

Wide particle concentration range from 0.1 ppm to 200,000 ppm (20%)
• Ideal for paste or changeable samples by dilution​​​​​

Continuous measurement function at minimum 1-second intervals
• Ideal for samples that change over time (shifts in the dispersion status)

Wide measurement range from 15µL to 300mL
• Ideal for small-volume sample measurement​

Compatible with data integrity requirements
• Support for LabSolutions system with its proven compatibility with ER/ES regulations (only for SALD-2300)​

 

Aggregates Sizer

Aggregates Sizer ​​

Measures the concentration of 100nm to 10µm aggregates of biopharmaceuticals ​​
• Measures aggregates with small sample amounts
• Quantitative evaluation of the aggregation process with the real-time measurement function
• Temperature control function (when equipped with the Aggregates Sizer TC temperature control function)

2. Comparison Table

 

Model iSpect DIA-10 SALD-2300 SALD-7500nano​ Aggregates Sizer​

Measurement principle
Dynamic image analysis method
Laser diffraction method
Laser diffraction method
Laser diffraction method

Definition of particle size

Geometrical ​
(equivalent area diameter, maximum particle diameter, etc.)
Equivalent spherical diameter

Equivalent spherical diameter
​

Equivalent spherical diameter
​

Measurement range

5 to 100 μm
0.017 to 2,500 μm
0.007 to 800 μm
100 nm to 10 μm

Measurement method

• Wet measurement

• Wet measurement
• Dry measurement
• High concentration measurement

• Wet measurement
• High concentration measurement

• Wet measurement

Particle count measurement

Yes
No
No
Yes*

Shape observation and analysis

Yes
No
No
No

Distribution basis
Count basis
Volume basis
Volume basis
Volume basis

Measurement time

10 mins
10 secs
10 secs
10 secs

Features

• Can confirm particle shape
• Can identify a small amount of particles
• Can evaluate single particle or aggregate
• Wide measurement range
• Short measurement time
• Wide range of sample types
​
• Wide measurement range
• Short measurement time

 

*For biopharmaceuticals only. Conversion from volume concentration to number concentration.

3. Lectures on Particle Size Analysis

 

Fundamentals of Particle Size Analysis
Lecture on Particle Analysis - Beginners' Course
Lecture on Particle Analysis - Hands-on Course
Lecture on Particle Analysis - Intermediate Course
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