An Examination of the Effects of High/Low Column Cooling Rates Using Nexis™ GC-2030

Introduction

Gas chromatography is a technique for separating components within a sample by utilizing the adsorption and desorption of components from a column when it is heated. The adsorption and desorption differ according to the column's liquid phase type. After analysis, the column must be cooled down to the initial temperature, but the rate at which the column is cooled may affect the column's liquid phase. Until now, priority was placed on shortening cooling times in order to shorten analysis cycles. However, the Nexis GC-2030 now allows operators to select a column cooling rate of their choice. By selecting the optimum cooling rate, the life time of the column can be maximized. This article compares the baseline noise and the S/N ratio of peaks according to different cooling rates when using the Nexis GC-2030 cooling program.

June 25, 2023 GMT