Nexera ASAPrep - Configuration

Analytical to Preparative Scale-up System

System Contents

Analytical System: For Screening Analysis

Nexera XR and LCMS-2050 unit

Nexera XR and LCMS-2050 units

This Nexera ASAPrep-compatible system is configured with Nexera XR and LCMS-2050 units.
The system uses built-in solvent and column-switching valves to screen samples based on either acidic or basic conditions.

Preparative System: For Purification Analysis

Nexera Prep and LCMS-2050 unit

Nexera Prep and LCMS-2050 unit

This Nexera ASAPrep-compatible system is configured with Nexera Prep and LCMS-2050 units.
The system uses built-in solvent and column-switching valves to switch between acidic and basic conditions. Optimized preparative condition are generated and executed based on screening results.

Shim-pack Scepter™

The columns used in the Nexera ASAPrep system must allow the use of acidic and basic mobile phases across a wide pH range, and enable seamless scale-up from analytical to preparative analysis.
Shim-pack Scepter C18 columns are packed with an organic silica hybrid base material that provides excellent pH resistance, allowing them to be used with the wide pH range required by the Nexera ASAPrep system. The standard method included with Nexera ASAPrep systems has been optimized using the Shim-pack Scepter C18 column.

Open Solution

Open Solution software enables efficient analysis by multiple users sharing the same system in a research laboratory. It supports both LC and LC–MS analysis, allowing users to efficiently perform qualitative analysis and scale-up to purification simply by selecting from preset methods.
Remote data analysis using a personal computer helps minimize the exclusive use of analytical computers. Furthermore, built-in functionality helps maintain system performance.

Nexera, ASAPrep, and Shim-pack Scepter are registered trademarks of Shimadzu Corporation or its subsidiaries in Japan and/or other countries.