Nexera ASAPrep
Analytical to Preparative Scale-up System
Unique Algorithm Increases Efficiency of Compound Purification
During compound synthesis, both the target product and impurities are generated. These impurities must be removed in a subsequent purification step to ensure sufficient purity for actual use. Preparative liquid chromatography (preparative LC) is commonly used for this process. However, because it requires specialized expertise and takes a significant amount of time, there is a clear need to improve efficiency. The Nexera™ ASAPrep™ (automated scaling-up from analytical to preparative chromatography) system is equipped with a unique algorithm that automatically evaluates the complexity of preparative chromatography and generates optimal conditions. Furthermore, an intuitive UI design enables easy purification by anyone, regardless of experience level. Because the system is able to help assign purification tasks depending on the difficulty level, it can enable a more efficient purification workflow.

Nexera, ASAPrep, is registered trademarks of Shimadzu Corporation or its subsidiaries in Japan and/or other countries.
Features
News / Events
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Recommended Reading: AI, Automation, and the Future of Drug Discovery Description
In this Drug Discovery News interview, Raymond Wong of Shimadzu UK shares insights into how AI-enabled workflows, connected data, and laboratory automation are helping accelerate pharmaceutical research and development.
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Shimadzu has released the Nexera X4 Ultra High Performance Liquid Chromatograph.
Expanding on technologies cultivated with previous Nexera series models, the next-generation Nexera X4 ultra high performance liquid chromatograph (UHPLC) achieves an incomparable level of analytical performance. The lowest degree of peak broadening* in the industry results in ultra-sharp peaks and outstanding separation performance while cutting-edge fluid control technology provides exceptional solvent delivery consistency, even for fast analysis under ultra-high-pressure conditions, and highly reliable results. Engineered with precision, the high-end Nexera X4 UHPLC offers new value for all laboratories that demand maximum performance.
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Nexera IC Ion Chromatograph has been released.
The Nexera IC ion chromatograph combines a compact footprint with uncompromising performance, enabling anyone to perform analysis effortlessly and efficiently.
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PL-40, Automation-Compatible Plate Loader for LC/LC-MS Systems has been released
The PL-40 solves for LC/LC-MS automation, it seamlessly loads plates of pretreated samples into an LC/LC-MS system, enabling a fully automated workflow, from pretreatment to analysis.
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New Technical Report is available, Optimization of Supercritical Fluid Extraction Parameters for Vitamins D2, D3, and K1 from Pharmaceutical Preparations
New Technical Report is available, Optimization of Supercritical Fluid Extraction Parameters for Vitamins D2, D3, and K1 from Pharmaceutical Preparations
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New Tips & Tricks is available, Automated Dilution and Preparation of Standard and Sample Solutions for Analysis