MALDI-TOF MS Comparison

This page provides a quick overview of 7 models of MALDI/MALDI-TOF mass spectrometers. Choose the model that best suits your analysis needs from the compact digital ion trap MS for on-the-spot analysis, the benchtop MALDI-TOF MS for routine analysis to the research grade MALDI TOF/TOF MS for a diverse range of applications.
 

 

Contents

1. Summary of Product Features​

 

MALDImini-1

MALDImini-1
MALDI digital ion trap mass spectrometer​

“Minimum” footprint
With its simple configuration and compact size, it is possible to install the MALDImini-1 in places where mass
analysis devices could not previously be used. 

“Minimum” time
​Miniaturization allows rapid, "on-the-spot" analysis and simplifies data acquisition.

“Minimum” sample volume
Complex structural analysis can be performed even with sub-µL sample volumes.

 

MALDI-8030

MALDI-8030​
Dual-polarity benchtop linear MALDI-TOF MS​​

Best-in-class sensitivity and resolution
Easily detect analytes for your application

Quickest to your result
Fast (200 Hz) solid-state laser and fast sample instruction using load-lock chamber

​​Small footprint/benchtop design
The smallest instrument in its class – saves your valuable laboratory space

Solutions for all your applications
Food & cosmetics, teaching & research labs, regulatory & manufacturing Labs

 

MALDI-9030

MALDI-7090
MALDI-TOF MS​​​

High throughput and high resolution
True 2kHz acquisition speed in MS and MS/MS modes and high MS/MS resolution (10,000) via ASDF

Hyper-MS2, a new benchmark in MS/MS acquisition
Combining core technologies patented and exclusive to Shimadzu

Ultimate applications performance
Flexibly accommodate a wide range of analysis needs 

 

 

AXIMA Performance

AXIMA Performance
MALDI TOF/TOF mass spectrometer

Highly flexible research-grade MALDI TOF/TOF mass spectrometer
From high energy MS/MS of proteomics and other biological and organic samples to uncompromised analysis of high mass intact proteins

High performance in a robust and flexible design
Uncompromised linear mode performance for high mass analysis

Application-centric solutions
Provides total support for protein identification, LC-MALDI and biomarker discovery

 

2. ​Comparison Table

Specifications

 
Measurement
type
Digital Ion Trap
Linear-TOF Linear-TOF Linear/Reflectron-TOF
Reflectron-TOF/TOF
Linear/Reflectron-TOF Linear/Reflectron-TOF
Reflectron-TOF/TOF
Linear/Reflectron-TOF
Reflectron-TOF/TOF
Measured
ion
Positive
Positive
Positive and Negative
Positive and Negative
Positive and Negative Positive and Negative Positive and Negative
Mass range (m/z) 650-70,000
1-500,000
(Linear mode)
1-500,000
(Linear mode)
1-500,000
(Linear mode)
1-80,000 (Reflectron mode)
1-500,000
(Linear mode)
1-500,000
(Linear mode)
1-80,000 (Reflectron mode)
1-500,000
(Linear mode)
1-80,000 (Reflectron mode)
MS/MS function CID
up to MS3
 -
 -
CID/PSD
(Post Source Decay)
 - Post Source Decay
(PSD)
CID
Mass Resolution > 4,000
> 5,000
> 5,000
> 6,000
(Linear mode)
> 25,000 (Reflectron mode)
> 10,000 (MS/MS)
> 5,000 > 5,000
(Linear mode)
> 15,000 (Reflectron mode)
> 5,000
(Linear mode)
> 20,000
(Reflectron mode)
Mass accuracy External : 200 ppm
Internal : 20 ppm
External : 200 ppm
Internal : 20 ppm
External : 200 ppm
Internal : 20 ppm
(Refrectron mode)
50 ppm
(Linear mode)
Internal : <30 ppm
External: <200 ppm
Internal : 10 ppm
(Refrectron mode)
30 ppm
(Linear mode)
Internal : 5 ppm
(Refrectron mode)
30 ppm
(Linear mode)
Throughput 0.3, 0.6 spectrum/s (Depend on mass range and scan speed)
50, 100, 200Hz (Variable)
50, 100, 200Hz (Variable)
1 - 2,000 Hz (Variable) 1 - 50 Hz (Variable) 1 - 50 Hz (Variable)
1 - 50 Hz (Variable)
Dimensions/ Weight W309 × D385
× H320 mm
25 kg
W600 × D745
× H1,055 mm
86 kg
W600 × D745
× H1,055 mm
92 kg
W2,834 × D1,276
× H1,182 mm
875 kg
W700 × D850
× H1,920 mm
330 kg
W700 × D850
× H1,920 mm
345 kg
W700 × D850
× H1,920 mm
375 kg
Type Benchtop
Benchtop
Benchtop
Floor standing
Floor standing
Floor standing
Floor standing

Applications

 
Protain identification
sample
           
Glycans/
Glycopeptides investicgation
sample
 
 
 
     
Synthetic peptides and Proteins  
sample
sample
       
Screening analysis  
sample
sample
       
Cell culture  
sample
sample
sample
     
Food/
Cosmetics
 
sample
sample
sample
     
Small molecules  
sample
sample
     
sample
QA/QC  
sample
sample
     
sample
Polymer analysis  
sample
sample
sample
 
sample
sample
Oligonucleotide/ Primer analysis    
sample
   
sample
sample
Biomarker
discovery
         
sample
 
Proteomics          
sample
 
High-energy MS/MS of proteomics and other biological /Organic samples      
sample
sample
   
High-mass intact proteins      
sample
sample
   
MS Imaging      
sample
     
High thoughput screening      
sample
     
 

3. Principle of MADI-TOFMS​

What is MALDI ?

What is MALDI?

MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization."
The sample for MALDI is uniformly mixed in a large quantity of matrix…

 

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