MALDI-Based Instruments Comparison
MALDI-Based Instruments Comparison
This page provides a quick overview of 7 models of MALDI-Based Instruments. Choose the model that best suits your analysis needs from the compact digital ion trap MS for on-the-spot analysis, the benchtop MALDI-TOF MS for routine analysis to the research grade MALDI TOF/TOF MS for a diverse range of applications.
Contenido
1. Resumen de las características del producto
“Minimum” footprint
With its simple configuration and compact size, it is possible to install the MALDImini-1 in places where mass
analysis devices could not previously be used.
“Minimum” time
Miniaturization allows rapid, "on-the-spot" analysis and simplifies data acquisition.
“Minimum” sample volume
Complex structural analysis can be performed even with sub-µL sample volumes.
Best-in-class sensitivity and resolution
Easily detect analytes for your application
Quickest to your result
Fast (200 Hz) solid-state laser and fast sample instruction using load-lock chamber
Small footprint/benchtop design
The smallest instrument in its class – saves your valuable laboratory space
Solutions for all your applications
Food & cosmetics, teaching & research labs, regulatory & manufacturing Labs
Highly flexible research-grade MALDI TOF/TOF mass spectrometer
From high energy MS/MS of proteomics and other biological and organic samples to uncompromised analysis of high mass intact proteins
High performance in a robust and flexible design
Uncompromised linear mode performance for high mass analysis
Application-centric solutions
Provides total support for protein identification, LC-MALDI and biomarker discovery
Especificaciones
| Benchtop Instruments | Floor Standing Instruments | |||||
|---|---|---|---|---|---|---|
| Measurement type |
Digital Ion Trap
|
Linear-TOF | Linear-TOF | Linear/Reflectron-TOF | Linear/Reflectron-TOF Reflectron-TOF/TOF |
Linear/Reflectron-TOF Reflectron-TOF/TOF |
| Measured ion |
Positive
|
Positive |
Positive and Negative
|
Positive and Negative | Positive and Negative | Positive and Negative |
| Mass range (m/z) | 650-70,000 |
1-500,000
（Linear mode） |
1-500,000
（Linear mode） |
1-500,000 （Linear mode） |
1-500,000 （Linear mode） 1-80,000 (Reflectron mode) |
1-500,000 （Linear mode） 1-80,000 (Reflectron mode) |
| MS/MS function | CID up to MS3 |
-
|
-
|
- | Post Source Decay (PSD) |
CID |
| Mass Resolution | > 4,000 |
> 5,000
|
> 5,000
|
> 5,000 | > 5,000 （Linear mode） > 15,000 (Reflectron mode) |
> 5,000 （Linear mode） > 20,000 (Reflectron mode) |
| Mass accuracy | External : 200 ppm |
Internal : 20 ppm
External : 150 ppm |
Internal : 20 ppm
External : 150 ppm |
Internal : <30 ppm External: <200 ppm |
Internal : 10 ppm (Refrectron mode) 30 ppm (Linear mode) |
Internal : 5 ppm (Refrectron mode) 30 ppm (Linear mode) |
| Throughput | 0.3, 0.6 spectrum/s (Depend on mass range and scan speed) |
50, 100, 200Hz (Variable)
|
50, 100, 200Hz (Variable)
|
1 - 50 Hz (Variable) | 1 - 50 Hz (Variable) |
1 - 50 Hz (Variable)
|
| Dimensions/ Weight | W309 × D385 × H320 mm 25 kg |
W600 × D745
× H1,055 mm 86 kg |
W600 × D745
× H1,055 mm 92 kg |
W700 × D850 × H1,920 mm 330 kg |
W700 × D850 × H1,920 mm 345 kg |
W700 × D850
× H1,920 mm 375 kg |
| Ion Source Maintenance | - |
・TrueClean automated source cleaning
・Manual ion source cleaning (EasyCare only) |
・TrueClean automated source cleaning
・Manual ion source cleaning (EasyCare only) |
- |
-
|
-
|
Aplicaciones
| Benchtop Instruments | Floor Standing Instruments | |||||
|---|---|---|---|---|---|---|
| Peptide mass fingerprinting |
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| Protein sequencing |
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| Glycans/ Glycopeptides investicgation |
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| Synthetic peptides and Proteins | |
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| Screening analysis |
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| Cell culture | |
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| Food/ Cosmetics |
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| Small molecules |
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| QA/QC |
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| Polymer analysis |
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| Oligonucleotide/ Primer analysis | |
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| Biomarker discovery |
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| Proteómica | |
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| High-energy MS/MS of proteomics and other biological /Organic samples |
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| High-mass intact proteins | |
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| MS Imaging | |
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3. Principle of MADI-TOFMS
What is MALDI?
MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization."
The sample for MALDI is uniformly mixed in a large quantity of matrix…
Noticias/eventos
-
CONFERENCIA INTERNACIONAL DE ESPECTROMETRÍA DE MASAS 2024
Visite el stand de Shimadzu en la Conferencia Internacional de Espectrometría de Masas (IMSC) 2024.
-
Maldi EasyCare Training Video has been uploaded.
The Shimadzu MALDI EasyCare solution offers a convenient way to perform routine maintenance on your system and increase your uptime. Manual cleaning of ion optics is safe, quick (period from venting to ion optics removal is approx. 10 mins), easy-to-do requiring no tools (except single-point use of flat blade screwdriver) and no technical expertise due to full guidance by software wizard. All cleaning materials provided.
-
Shimadzu has released the MALDI-EasyCare, Upgrade for the MALDI-8000 Series MALDI-TOF mass spectrometers
Maintain optimal performance of your system using MALDI EasyCare to manually clean the ion optics and autotune the instrument.
-
Shimadzu has released the FlexiFocus™
The FlexiFocus adaptor has been specifically designed to hold a FlexiFocus insert and position it optimally for analysis in the Shimadzu MALDI-8020 and MALDI-8030 benchtop MALDI-TOF instruments.
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Latest issue of Shimadzu Journal, featuring Forensics / Toxicology, has come out.
This issue focuses on "Forensics / Toxicology", an area where science and technology are particularly important and needed. It starts with two customer interviews.
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Life Science Biomarker Industry Page has been updated
Biomarkers are derived from living organisms and found in tissues, blood, and other bodily fluids. Biomarkers are indicators of biological changes in an organism and are used to diagnose disease, in prognosis, and to evaluate the efficacy and safety of pharmaceuticals. Biomarkers can be nucleic acids, proteins, peptides, lipids, and sugars, and are identified using various “omics” techniques.