Fully Automated Sample Preparation Module for LCMS


Fully automated sample preparation module for LCMS based on Shimadzu's extensive experience manufacturing clinical systems that perform blood coagulation analysis.

Simply place blood collection tubes in position and the module automatically performs sample pretreatment steps up to LC/MS/MS analysis.





About CLAM-2030

Due to superior specificity, leading to better analytical accuracy and precision, liquid chromatograph mass spectrometers (LC-MS/MS) have started to be used for confirmatory measurements of drugs, steroids, and vitamin D. Manual sample preparation procedures can lead to variations and mistakes, often due to the procedure being used or an operator’s inexperience. Connecting a fully automated CLAM-2030 to an LC-MS/MS system minimizes these issues, enabling fully automated and highly accurate analysis throughout the entire process – from pretreatment to LC/MS/MS measurement – using touch-panel software operation.


Reliable Data Acquisition

  • Fully automates processes from pretreatment to LC/MS/MS analysis.

  • Reduces variability in internal standard substance concentration (using vials with septa installed).

  • Equipped with a full range of accuracy control functions.

  • Reduces operator errors.


Eliminates the Need to Review Settings for Routine Work

  • Automates processes from searching toxicological drug libraries to generating reports.*1

  • Provides the optimal analytical method.*2


Improves Efficiency of Processes

  • Makes it easy to create or review new pretreatment protocols.

  • Samples can be added or processing interrupted in an emergency.*3

  • Text files can be used to load analysis requests from a LIS or output concentration values to a specified folder.






*1: Requires the LC/MS/MS forensic toxicological database or rapid toxicology screening system ver. 3, which are sold separately.
*2: Limited to commercial LC/MS/MS analysis kits and other methods available for supply.
*3: The number of interruptions or samples that can be added is limited by the number of pretreatment vials placed.


CLAM, LC/MS/MS, Nexera, UFsweeper, UF-Qarray, and Synchronized Servey Scan are trademarks of Shimadzu Corporation. Vacutainer is a registered trademark of Becton, Dickinson, and Company. VENOJECT is a registered trademark of Terumo Corporation.


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