Nexera series - Applications

Ultra High Performance Liquid Chromatograph

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Fully Automated Workflow for HPLC Analysis Using Automatic Startup with FlowPilot Function

An appropriate start-up procedure, a warm-up of the LC system and a specific System Suitability Test (SST) are critical steps before any analytical LC session in order to ensure high data quality in terms of reproducibility, accuracy, etc., and to reduce maintenance costs (e.g. by prolonging the lifetime of analytical columns). These procedures are often time-consuming for operators, and, if not performed properly, can lead to the loss of data and the waste of time and resources due to the need for re-analysis. In this report, we explain the ways in which we have improved and completely automated system startup and SST through a combination of different technologies

Use of Solvent Delivery Unit Equipped with Auto-diagnostics and Auto-recovery Functions to Enhance Lab Productivity

In order to improve productivity in modern analysis laboratories, it is essential to reduce analysis time and maximize throughput through regular maintenance. One issue to be resolved is the interruption of analysis due to unforeseeable problems. An example of this is air bubbles in the flow line, which can cause shifts in retention times, pulsating baselines, unexpected changes in peak shapes. In this report, we describe the effectiveness of auto-diagnostics and auto-recovery functions in detecting and resolving this problem automatically. These functions minimize system downtime due to air bubbles and contribute to the optimization of laboratory productivity.

The Latest Applications

Using i-PeakFinder™, an Automatic Peak Integration Algorithm, to Provide Labor Savings and Improve the Efficiency of Analytical Operations -Example of its Application to Organic Acid Analysis-

Technical Report

Using i-PeakFinder™, an Automatic Peak Integration Algorithm, to Provide Labor Savings and Improve the Efficiency of Analytical Operations -Example of its Application to Organic Acid Analysis-

New Analytical Intelligence Concept - Support for Automating Analytical Operations

Technical Report

New Analytical Intelligence Concept - Support for Automating Analytical Operations

Analysis of Meloxicam in Accordance with the United States Pharmacopoeia by Nexera™ XR

Application News

Analysis of Meloxicam in Accordance with the United States Pharmacopoeia by Nexera™ XR

Fermentation Processes Monitoring Using a Nexera™ Dual Injection System

Application News

Fermentation Processes Monitoring Using a Nexera™ Dual Injection System

 

Technical Report

  • Eliminating the Effects of Room Temperature Fluctuations Using the Advanced TC-Optics Function in the SPD-M40 Photodiode Array Detector - Improving Baseline Stability and Analytical Precision
  • Improving Peak Shape Using the Automatic Pretreatment Function (Co-Injection) in the SIL-40 Series Autosamplers
  • Heightened Analytical Efficiency and Integrated Management of Multifaceted Data Using the Dual Injection Function in the SIL-40 Series Autosampler
  • Increased Analysis Throughput by Overlapped Injection Using the SIL-40 series Autosampler
  • Ultra-Fast Analysis of Drugs in Biological Fluids with the SIL-40 Autosampler
  • Improved Linearity and Quantification Using the SPD-M40 Photodiode Array Detector
  • Fully Automated Workflow for HPLC Analysis Using Automatic Startup with FlowPilot Function - Analytical Intelligence Part 3 -
  • Maximizing Analytical Efficiency with Real-time Measurement of Mobile Phase Consumption - Analytical Intelligence Part 2 -
  • Use of Solvent Delivery Unit Equipped with Auto-diagnostics and Auto-recovery Functions to Enhance Lab Productivity - Analytical Intelligence Part 1 -

Application News

Pharmaceutical

  • High-Speed Analysis of Linezolid following the Draft Guidance of International Harmonization of Pharmacopoeias
  • Improvement of Quantitative Performance for Ibuprofen Using UV Cut-Off Filter on SPD-M40
  • Impurity Analysis in Pharmaceutical Products with the Advanced Photodiode Array Detector SPD-M40

Food

  • Monitoring Organic Acids during Fermentation with Shim-packTMFast-OA High-Speed Organic Acid Analytical Colum
  • High-Speed Analysis of Methylated Catechin in Benifuuki Green Tea
  • Simple and Quick Analysis of Theanine in Tea by Automatic Pre-Column Derivatization Method
  • Analysis of Nucleic Acid Related Substances in Fish Meat and Automatic Calculation of Freshness (K Value) Using Multi-Data Report Function

Chemical

  • Qualitative Analysis of UV-Absorbents in Cosmetics Based on UV-Vis Spectrum
  • Increased throughput with Nexera™ GPC system: Overlapped Injection and Simultaneous Determination of Polymer Additives
  • High-Resolution and High-Speed Simultaneous Analysis of Regulated UV-Adsorbents in Cosmetics using SPP Column
  • High-resolution and high-speed simultaneous analysis of preservatives in cosmetics using SPP column