CellTune Ver.2 Software for Supporting Optimization of Cell Culture Conditions
To achieve bioproduction that is both cost-efficient and high in quality, it is important to optimize parameters, such as the culture medium composition and culturing environment. However, the vast number of possible parameter combinations makes comprehensive optimization difficult. CellTune, software designed to support the optimization of cell culture conditions, uses statistical analysis to identify culture-medium components requiring optimization and proposes optimized conditions for the selected components. This approach enables efficient optimization of culturing parameters regardless of operator experience or expertise level.
CellTune includes two main functions: a feature extraction module and an AI automatic optimization module. The feature extraction module can identify the components that are important for cell culturing based on statistical analysis of cell culture solution monitoring data obtained by LC-MS analysis. The AI automatic optimization module uses a sequential optimization method to efficiently explore optimal conditions for important components and environmental parameters.