Applications of Stable Isotope Analysis

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Stable isotope-labeled standards are widely used for quantitative mass spectrometry. This page highlights LC-MS/MS applications using stable isotope-labeled standards in clinical research and forensic toxicology, pharmaceutical and biopharmaceutical analysis, and environmental analysis.

Clinical Research and Forensics
Fast Profiling of 39 Bile Acids in Plasma, Urine and Feces, by Automated Extraction and LCMS-8060NX
Measuring Choline and its Metabolites in Human Plasma Using an LC/MS/MS System with Fully Automated Sample Preparation Module
Simultaneous Analysis of Remdesivir and Metabolites in Human Plasma Using Fully Automated Sample Preparation LC/MS/MS System
Simultaneous Analysis of Remdesivir and Metabolites in Human Plasma
Analysis of Favipiravir in Human Plasma
Analysis of Favipiravir in Human Plasma Using Fully Automated Sample Preparation LC/MS/MS System
Analysis of PFAS Specified in EPA Method 537 and Beyond using Shimadzu UFMS
Pharmaceutical and Biopharmaceutical
Rapid Analysis of Anticoagulants in Plasma Using LC-MS/MS
Quantitation of 7 N-nitrosamines in Monoclonal Antibody (mAb) Formulations Using LC-MS/MS
Environment 
Analysis of Per- and Polyfluoroalkyl Substances (PFAS) Specified in EPA M537.1 Using the Triple Quadrupole LCMSTM-8045
Determination of various PFAS in drinking water using on-line SPE coupled to LC-MS/MS

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