Triple Quadrupole LC-MS/MS Comparison

Triple quadrupole mass spectrometry (TQMS) is a versatile tool for quantitative analysis. Experience the excellent performance and robustness of Shimadzu’s LCMS-TQ instruments, which offer a choice of speed, sensitivity and resolution to meet the demands of high-throughput routine analysis and/or more specialized applications.

Compare Shimadzu’s triple quadrupole LC-MS/MS systems below.

LC-MS basic guide

Triple Quadrupole LC-MS/MS Comparison

		LCMS-8060NX	LCMS-8060	LCMS-8050	LCMS-8045	LCMS-8040
Features		On top of the architecture of the LCMS-8060, it adds flexibility in optimizing parameters to achieve unsurpassed sensitivity. New ion optic components all increase robustness without compromising on a high ion transmission rate.	A new vision in sensitivity. It is suitable for drug discovery, manufacturing, clinical research, food safety, environmental, or drugs-of-abuse analysis.	The first mass spectrometer to achieve a scan speed of 30,000 u/sec and 5 msec polarity switching time. It boasts the ideal balance of good data quality, high throughput and affordability for a wide range of challenging and routine applications.	Designed specially for robust data acquisition with best-in-class sensitivity. It withstands long periods of continuous operation in laboratories in demand of reliable data.	Introduces the new UF-Lens™ and UFsweeper™ II, the hallmark technologies underlying fast ion transmission and high sensitivity.
Sensitivity (S/N)
Scan Speed
Ionization Unit Compatibility	ESI
	APCI
	DUIS*¹⁾
	Heated-ESI
	Heated-ESI with IonFocus
	Micro-ESI
	Probe-ESI
Measurement Mode	Q1 Scan/SIM
	Q3 Scan/SIM
	MRM
	Precursor ion scan
	Product ion scan
	Neutral loss scan
	Synchronized Survey Scan™*²⁾
Collision Cell		UFsweeper III*³⁾	UFsweeper III*³⁾	UFsweeper III*³⁾	UFsweeper II*³⁾	UFsweeper II*³⁾
		LCMS-8060NX	LCMS-8060	LCMS-8050	LCMS-8045	LCMS-8040

DUIS: The dual ion source continuously performs both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).
Synchronized Survey Scan: Synchronized Survey Scan (SSS) automatically performs a product ion scanning whenever a pre-set survey scan threshold is exceeded.
UFsweeper: UFsweeper is a unique technology that delivers unparalleled efficiency and speed. UFsweeper accelerates ions out of the collision cell by forming a pseudo-potential surface.

Application Specific LC-MS Systems Products

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