Triple Quadrupole LC-MS/MS Comparison
Triple quadrupole mass spectrometry (TQMS) is a versatile tool for quantitative analysis. Experience the excellent performance and robustness of Shimadzu’s LCMS-TQ instruments, which offer a choice of speed, sensitivity and resolution to meet the demands of high-throughput routine analysis and/or more specialized applications.
Compare Shimadzu’s triple quadrupole LC-MS/MS systems below.
Triple Quadrupole LC-MS/MS Comparison
| LCMS-8060NX | LCMS-8060 | LCMS-8050 | LCMS-8045 | LCMS-8040 | ||
|---|---|---|---|---|---|---|
| Features | On top of the architecture of the LCMS-8060, it adds flexibility in optimizing parameters to achieve unsurpassed sensitivity. New ion optic components all increase robustness without compromising on a high ion transmission rate. | A new vision in sensitivity. It is suitable for drug discovery, manufacturing, clinical research, food safety, environmental, or drugs-of-abuse analysis. | The first mass spectrometer to achieve a scan speed of 30,000 u/sec and 5 msec polarity switching time. It boasts the ideal balance of good data quality, high throughput and affordability for a wide range of challenging and routine applications. | Designed specially for robust data acquisition with best-in-class sensitivity. It withstands long periods of continuous operation in laboratories in demand of reliable data. | Introduces the new UF-Lens™ and UFsweeper™ II, the hallmark technologies underlying fast ion transmission and high sensitivity. | |
| Sensitivity (S/N) |  |
|
 |
 |
 |
|
| Scan Speed | |
|
|
|
|
|
| Ionization Unit Compatibility | ESI |
 |
||||
| APCI |
|
|
|
|
|
|
| DUIS*1) |
|
|
|
|
|
|
| Heated-ESI |
|
|
|
|
||
| Heated-ESI with IonFocus |
|
|||||
| Micro-ESI |
|
|
|
|
||
| Probe-ESI |
|
|
|
|
|
|
| Measurement Mode | Q1 Scan/SIM |
|
|
|
|
|
| Q3 Scan/SIM |
|
|
|
|
|
|
| MRM |
|
|
|
|
|
|
| Precursor ion scan |
|
|
|
|
|
|
| Product ion scan |
|
|
|
|
|
|
| Neutral loss scan |
|
|
|
|
|
|
| Synchronized Survey Scan™*2) |
|
|
|
|
|
|
| Collision Cell | UFsweeper III*3) | UFsweeper III*3) | UFsweeper III*3) | UFsweeper II*3) | UFsweeper II*3) | |
| LCMS-8060NX | LCMS-8060 | LCMS-8050 | LCMS-8045 | LCMS-8040 | ||
- DUIS: The dual ion source continuously performs both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).
- Synchronized Survey Scan: Synchronized Survey Scan (SSS) automatically performs a product ion scanning whenever a pre-set survey scan threshold is exceeded.
- UFsweeper: UFsweeper is a unique technology that delivers unparalleled efficiency and speed. UFsweeper accelerates ions out of the collision cell by forming a pseudo-potential surface.
Application Specific LC-MS Systems Products
News / Events
-
Life Science Biomarker Industry Page has been updated
Biomarkers are derived from living organisms and found in tissues, blood, and other bodily fluids. Biomarkers are indicators of biological changes in an organism and are used to diagnose disease, in prognosis, and to evaluate the efficacy and safety of pharmaceuticals. Biomarkers can be nucleic acids, proteins, peptides, lipids, and sugars, and are identified using various “omics” techniques.
-
Life Science Proteomics Industry Page has been updated
Proteomics is an academic discipline involving the comprehensive study of protein structure and function, typically by mass spectrometry and electrophoresis. Unlike the genome, the cells of an organism do not all contain the same complement of proteins, but different cells contain different proteins at different times. Proteomics uses this phenomenon to enable more efficient drug development and to determine the mechanisms of disease.
-
Cellulose nanofibers
Given that cellulose nanofibers（CNFs）offer attractive physical characteristics, such as light weight, strength, and hardness, they not only enable materials with advanced functionality, but are expected to be used as a reinforcing material that can reduce the weight of composite materials.
-
Handbook of Analysis Procedures for EPA method 533, EPA method 537.1 are now available.
The validity of the analysis performed by each laboratory needs to be confirmed by Quality Control (QC). This article section shows the general analytical procedure for fulfilling QC requirements. Note that the procedure could be modified depending on the situation in the lab and analysts.
-
Shimadzu has released the CLAM-2040, Fully Automated Sample Preparation Module for LCMS
The CLAM-2040 accompanies you on most of the analytical workflow and improves your overall throughput by drastically reducing the sample preparation time. Simply place the blood tubes in position and the CLAM-2040 performs the next steps automatically, from sample extraction, up to the LCMS analysis and data processing.
-
Per- and Polyfluoroalkyl Substances (PFAS)
Per-and polyfluoroalkyl substances (PFAS) are a group of persistent and harmful chemicals that can be commonly found in the environment globally. These anthropogenic chemicals can come from various sources such as manufacturing, industrial applications, food contact materials and consumer products, and eventually end up and accumulate in the water, soil and living organisms.