2023

To help achieve carbon neutrality, governments and companies around the world are pursuing initiatives for weight reduction and CASE (Connected, Autonomous, Shared, Electric) as a framework for next-generation automobiles. This e-book introduces a range of evaluation and analysis technologies that bolster the advancement of lightweight automobiles that exhibit CASE attributes.

The OAD-TOF system is a Q-TOF LCMS that realizes OAD (Oxygen Attachment Dissociation), Shimadzu's proprietary fragmentation technology. It allows the analysis of the position of carbon-carbon double bonds in lipids and other organic compounds. Combined with the LCMS-9050, which boasts world-class high mass accuracy and fast polarity switching, it enables the creation of innovative applications.

The next-generation GCMS-QP2050 gas chromatograph mass spectrometer, with its accumulation of impressive Shimadzu technology, will lead the way forward. New value is provided by hardware boasting astounding reliability and stability, and easy-to-operate software equipped with superior automated technology.

IRSpirit FTIR spectrophotometers are extremely compact, but can still be used with standard accessories from Shimadzu and other manufacturers. IRSpirit instruments come with IR Pilot software, which offers 23 application programs without the need for parameter setup. Measure multiple samples with just a few clicks.

The LC/MS/MS Method Package for Sugars and Sugar Nucleotides includes LC/MS/MS analytical methods with analytical conditions and MS parameter settings optimized for analyzing 25 different sugars, amino sugars, sugar acids and sugar alcohols, 9 different sugar nucleotides, related metabolites, and internal standards.

Even though Ethylene oxide (EtO / EO) is well-known to be a toxic compound with carcinogenic and mutagenic concerns, it has been widely used for fumigation in the food industry because it effectively reduces or eliminates microbiological contamination with bacteria/fungi. The recent recall of food products exported to the EU due to non-compliance with EU regulations has highlighted the importance of quantitation of EtO and 2-CE residues in food.

LabSolutions™ i-QLinks provides integrated control over the quality testing operations of an analytical laboratory, including the preparation of test plans and instructions, the incorporation of test results from analytical instruments such as HPLC, the automatic preparation of test reports from the incorporated test results, and the management of the quality test progress.

One of the appeals of Japanese sake is the wide variety of tastes and aromas (flavors) offered by sake brands and individual products. Sake makers want to be able to describe to consumers the unique flavor characteristics of sake brewed within a specific “terroir” in a way that is also easy to understand.

The HIC-ESP is a new anion suppressor ion chromatograph with built-in electrodialytic suppressor, boasting the same low carryover and excellent injection precision characteristic of Shimadzu HPLCs to bring you highly-reliable results. The newly developed anion suppressor prevents peak spreading and achieves high sensitivity, providing stable functionality even over long periods of use.

Inheriting the concept of a mass spectrometer equipped with an optical microscope from the iMScope series, the iMScope QT is also Shimadzu's flagship model for MS imaging with a LCMS-Q-TOF.

Carotenoids and their derivatives are versatile isoprenoids based on a C40 tetraterpenoid skeleton and play a vital role in plants and animals, but, due to their high variability in the chemical structures, isomerization, poor stability and lack of commercially available standards, their identication in real samples is a challenging task.

LabSolutions™ MD improves method development efficiency by taking an Analytical Quality by Design (AQbD) approach. This software efficiently develops highly reliable analysis methods by configuring mobile phases, columns, and other parameters using an analysis function that automatically generates analysis schedules with the experimental design method and a data analysis function that plots a design space and predicted chromatogram.

We interviewed Keiji Sumiya from the Japanese chemical manufacturer Showa Denko Materials Co., Ltd (At the time of the interview., currently, Resonac Holdings Corporation). Showa Denko Materials is a global company that offers one-stop solutions for a variety of challenges in fields ranging from advanced materials to technical services.

Preparative SFC is a groundbreaking separation and purification technology. It has a number of advantages in comparison to preparative LC including simplified posttreatment, shorter analysis times, and different separation selectivity. With preparative SFC, the injection of large sample volumes is often required in order to increase the recovered amount.

Synchronizes Third-Party Software for Pretreatment Units with Shimadzu LC and LC-MS

A Place to Create and Exchange New Knowledge, and Share It with the World

The approach for the SFC analytical condition development process is basically the same as for determining analytical conditions for HPLC.

"Smaller, simpler, and easier to use – without compromising performance." That’s the demand from analysts. And that’s why Shimadzu developed the Brevis GC-2050. This new space-saving GC delivers uncompromising analytical performance in a modern yet rugged design, easily meeting the analysis needs of laboratories in a range of industries.

The FlexiFocus adaptor has been specifically designed to hold a FlexiFocus insert and position it optimally for analysis in the Shimadzu MALDI-8020 and MALDI-8030 benchtop MALDI-TOF instruments.

The MAP-100 automates the typical steps needed to isolate microplastics. This improves the reproducibility of the analytical workflow, enables lab technicians to focus on other tasks, and makes handling of reagents safer.

This issue focuses on "Forensics / Toxicology", an area where science and technology are particularly important and needed. It starts with two customer interviews.

ICPMS-2040/ 2050 Series has achieved a harmonious blend of environmental-friendliness and analytical performance.

Genomics is an academic discipline that studies the structure (base sequence) and function of the genome. The term genome refers to all the genetic information in a cell and genomics studies the base sequence of this genetic information. Genomics elucidates genetic mechanisms by identifying the genes involved in a given mechanism and analyzing the functions and interactions of those genes.

Cell Pocket is an integrated system for both the analysis and management of cell images.

The catechin analysis kit, developed in collaboration with the National Agriculture and Food Research Organization (NARO), provides validated test methods for catechins in tea leaves and green tea drinks from sample pre-treatment to HPLC measurement. You can accurately quantitate the content of 11 catechins (including methylated catechins) and caffeine in tea leaves. This article summarizes the results of the catechins quantitation in several beverages: green tea, black tea, and oolong tea.

In recent years, identification and quantitation using pyrolysis-GC MS (Py-GC/MS) have been considered to evaluate the chemical properties of microplastics.

Xslicer SMX-6010 microfocus X-ray inspection system enables vertical CT imaging 3D Observation to Support Failure Analysis in the Electronics Industries.

This article describes a preparative online supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) system that combines an extraction step using supercritical carbon dioxide as the solvent, a separation step using supercritical carbon dioxide as the mobile phase, and a fractionation step using a preparative-scale fraction collector (FRC).

Glycomics is a field of study that analyzes carbohydrates comprehensively, mainly using mass spectrometry and sugar arrays. Although only nine types of monosaccharides exist in humans, various complex sugars such as glycoproteins, glycolipids and proteoglycans play important roles in aging and disease.

Perhaps you have heard of the term “bio-manufacturing.”
Biomanufacturing refers to the use of genetic technology to manufacture things, such as new kinds of materials, or to increase the yield of target materials produced by microorganisms. The research in this field that is being conducted around the world will lead to a shift away from dependence on fossil fuels and lead to resource autonomy. This will, in turn, result in solutions to global-scale societal issues, such as ocean pollution and food and resource shortages, while simultaneously achieve economic growth.

Soil pollution by pesticides sprayed with chemicals such as waste and heavy metals is recognized as one of the major environmental problems. In addition to direct contact with soil, drinking groundwater with toxic substances dissolved from contaminated soil can affect human health. Through soil analysis, we provide solutions to these environmental problems.

Shimadzu provides analytical equipment and solutions that can monitor not only the atmospheric environment, but also indoor working environments and direct emission sources. Here are some examples of measurements of inorganic and organic components in the air and indoor environment.

Peakintelligence for GCMS is equipped with new AI peak integration algorithms that significantly shorten the time needed for peak integration in the GC/MS/MS quantitative processing work sequence. AI algorithms trained with peak integration know-how provide peak integration on par with that of an experienced user, so configuring or adjusting parameters is not required. In addition, the software can correctly detect low-concentration samples.

Part1:
Latest Webinar: A Simple, Effective Solution for Characterization and Quantitation using Pyrolysis GC-MS.
Date: Tuesday, June 20, 2023
Time: 3:00 PM Eastern Daylight Time
Duration: 60 mins


Part2:
Latest Webinar:  Novel Microplastics Applications utilizing Pyrolysis GC-MS.
Date: Thursday, July 20, 2023
Time: 3:00 PM Eastern Daylight Time
Duration: 60 mins

UF-Amino Station, which was developed in collaboration with Ajinomoto Co., Ltd., uses a special high-speed and high-separation column and the LCMS-2020 mass spectrometer, to perform batch analyses of 38* amino acids and amino acid-related components in a mere 9 minutes.

The problem of waste is an unavoidable part of human social life. In addition to proper waste disposal, we must also promote the international promotion of the 3Rs, consisting of reuse, reduce, and recycle, toward a resource-recycling society. We are working to solve these waste problems by providing a variety of analytical methods.

LabSolutions Insight Biologics is a dedicated software platform for oligonucleotide characterization using the LCMS-9030 or LCMS-9050 quadrupole time-of-flight type (Q-TOF) mass spectrometer.

Per-and polyfluoroalkyl substances (PFAS) are a group of persistent and harmful chemicals that can be commonly found in the environment globally. These anthropogenic chemicals can come from various sources such as manufacturing, industrial applications, food contact materials and consumer products, and eventually end up and accumulate in the water, soil and living organisms.

Development of cell culture media and related analysis systems

Tm analysis systems can accelerate the development process and improve the quality of oligonucleotide therapeutics. Control by LabSolutionsTM software enables compliance with ER/ES-related regulatory requirements and improves the efficiency of analyzing the thermal stability (Tm analysis) of nucleic acids.

The Shimadzu LCMS-2050 High-Performance Liquid Chromatograph Mass Spectrometer and the AA-7800 series of atomic absorption spectrophotometers have received the Red Dot Design Award 2023.

Supports Fast and Convenient Quantitative Analysis of Catechins in Tea Leaves and Green Tea Beverages

How Syngenta is using UFPLC to extract and purify gram-scale by-products for regulatory testing

The Multi-omics Analysis Package is metabolic engineering software that can automatically generate metabolic maps and perform a variety of data analysis based on the vast amounts of mass spectrometry data generated in fields such as metabolomics, proteomics, and flux analysis.

The LC/MS/MS method package for steroid hormones contains LC/MS/MS analytical methods with optimized analytical conditions and MS parameters for analyzing 20 kinds of steroid hormones and corrective substances. The package enables comprehensive analysis of steroid hormones ranging from adrenocortical hormones, such as mineralocorticoid and glucocorticoid, to sex hormones, such as androgens, estrogens, and progestogens.

Latest Webinar: The Newest Alternative to Animal Testing for Skin Sensitization
Date: April 26, 2023
Time: 8:00 a.m. PDT, 11:00 a.m. EDT, 16:00 BST, 17:00 CEST
Duration: 60 mins

Semi-Preparative Supercritical Fluid Chromatography System

Nexera UC improves your analytical workflow by utilizing a completely new separation technology, Unified Chromatography, which unites sample separation, analysis with various separation modes, and high-sensitivity detection.

Biomarkers are derived from living organisms and found in tissues, blood, and other bodily fluids. Biomarkers are indicators of biological changes in an organism and are used to diagnose disease, in prognosis, and to evaluate the efficacy and safety of pharmaceuticals. Biomarkers can be nucleic acids, proteins, peptides, lipids, and sugars, and are identified using various “omics” techniques.

Proteomics is an academic discipline involving the comprehensive study of protein structure and function, typically by mass spectrometry and electrophoresis. Unlike the genome, the cells of an organism do not all contain the same complement of proteins, but different cells contain different proteins at different times. Proteomics uses this phenomenon to enable more efficient drug development and to determine the mechanisms of disease.

The World’s First Testing Machines Equipped with a Voice Operation Device

Given that cellulose nanofibers（CNFs）offer attractive physical characteristics, such as light weight, strength, and hardness, they not only enable materials with advanced functionality, but are expected to be used as a reinforcing material that can reduce the weight of composite materials.

Shimadzu has released Infrared Microscope AIMsight an automatic analysis system that can be used with confidence from your first analysis, equipped as standard with enhanced functionality to support analyses.

The Shimadzu imaging benchtop MALDI-TOF solution provides access for all to molecular imaging, through the introduction of a full imaging solution...

Shim-pack™ SUR-Na, a ligand exchange chromatography column, offers excellent performance by combining size exclusion mode and sodium-based ligand exchange mode to provide superior separation of sugar components. Pure water can be used for the mobile phase, resulting in less effort to prepare for the analysis.

Shimadzu has release new Shim-pack Scepter Series colmuns…

This article describes an example of using LabSolutions MD, a dedicated software for supporting method development, to automate pH screening by varying the mobile phase pH from 2.5 to 8.5 to evaluate the optimal pH level for separating 12 small-molecule drugs.