Small Molecule Pharmaceutical - Related Information

Solutions for Medicinal Chemistry [ PDF / 4.56MB ]

High-Speed Analysis of Linezolid following the Draft Guidance of International Harmonization of Pharmacopoeias - High Performance Liquid Chromatography [ PDF / 115.15KB ]

Introduction to MetID Solution Software for Structural Elucidation of Expected and Unexpected Metabolites - Technical Report vol.11 [ PDF / 967.76KB ]

Improvement of Productivity in Research on Intestinal Microbiota by Shim-pack™ Fast-OA High-Speed Organic Acid Analysis Column - High Performance Liquid Chromatography [ PDF / 78.01KB ]

Monitoring Organic Acids during Fermentation with Shim-pack™ Fast-OA High-Speed Organic Acid Analytical Column - High Performance Liquid Chromatography [ PDF / 219.03KB ]

Ultra Fast Method Scouting (2) - - Maximizing the Efficiency of Method Development [ PDF / 1.32MB ]

Improving Efficiency in the Preparation of Test Reports for Chemistry, Manufacturing, and Control (CMC) Using Multi Data Report [ PDF / 745.92KB ]

A New Peak Integration Algorithm for LabSolutions [ PDF / 637.92KB ]

Reaction Rate Analysis by Thermal Analysis [ PDF / 391.49KB ]

High Efficiency in Workflow from Preparative HPLC to Analytical HPLC by Nexera™ Prep System - High Performance Liquid Chromatography [ PDF / 359.34KB ]

USP-Compliant Analysis of Vitamins in Dietary Supplements Analysis of Calcium Pantothenate by Nexera™ XR - High Performance Liquid Chromatography [ PDF / 83.24KB ]

Evaluating the Performance of the LotusStream Gas-Liquid Separator for Preparative Supercritical Fluid Chromatography [ PDF / 1.20MB ]

Improved Efficiency of Isomer Preparative Operations by Supercritical Fluid Chromatography with Stacked Injection [ PDF / 554.12KB ]

Optimization of Analytical Conditions, and Scale-up from Analytical to Preparative Scale Using Supercritical Fluid Chromatography [ PDF / 506.29KB ]

Using i-PeakFinder™, an Automatic Peak Integration Algorithm, to Provide Labor Savings and Improve the Efficiency of Analytical Operations - -Example of its Application to Organic Acid Analysis- [ PDF / 568.88KB ]

Improving Peak Shape Using the Automatic Pretreatment Function (Co-Injection) in the SIL-40 Series Autosamplersceted Data Using the Dual Injection Function in the SIL-40 Series Autosampler [ PDF / 429.72KB ]

Ultra-Fast Analysis of Drugs in Biological Fluids with the SIL-40 Autosampler - - Analytical Intelligence Part 5 - [ PDF / 136.71KB ]

Measurement of Trace Heavy Metals in Food with Nutrient Function Claims by Microwave Digestion- Furnace Method [ PDF / 87.04KB ]

Fully Automated Workflow for HPLC Analysis Using Automatic Startup with FlowPilot Function - - Analytical Intelligence Part 3 - [ PDF / 351.23KB ]

Maximizing Analytical Efficiency with Real-time Measurement of Mobile Phase Consumption - - Analytical Intelligence Part 2 - [ PDF / 454.58KB ]

Analysis of Montelukast Sodium Using Prominence-i and Nexera-i MT - Analysis of Montelukast Sodium Using Prominence-i and Nexera-i MT [ PDF / 117.34KB ]

High Speed Analysis of Pharmaceutical Impurities in Compliance with European Pharmacopoeia Using Nexera-i MT - High Performance Liquid Chromatography [ PDF / 178.26KB ]

Improved Sample Pretreatment Using Offline Supercritical Fluid Extraction [ PDF / 810.16KB ]

Determination of MOSH Contamination in Baby Foods by Using LC-GC and LC-GCxGC-MS - Advances in food contaminant analysis [ PDF / 992.49KB ]

Analysis of Short-Chain Fatty Acids in Biological Samples Using GC-MS - Gas Chromatograph-Mass Spectrometry [ PDF / 190.18KB ]

An Examination of the Effects of High/Low Column Cooling Rates Using Nexis™ GC-2030 - Gas Chromatography [ PDF / 149.05KB ]

Detection of Protein Aggregates: Detection of Multimeric Proteins Using MALDI-TOF MS with a High Mass Detector - MALDI-TOF Mass Spectrometry [ PDF / 130.51KB ]

A workflow for identification of isobaric isoforms of glycans using off-line MALDI-MS system [ PDF / 416.28KB ]

Evaluation of the higher sensitive LC/MS/MS incorporates novel desolvation technologies to achieve low femto-gram LOQ [ PDF / 263.22KB ]

Screening analysis for drugs of abuse by LC-MS/MS enables fast polarity switching MRM triggered product ion scanning on the fly [ PDF / 302.81KB ]

Disulfide Bond Characterization of Monoclonal Antibody (mAb) Using Q-TOF Mass Spectrometer - Biopharma / LCMS-9030 (Q-TOF) [ PDF / 400.05KB ]

Analysis of Meloxicam in Accordance with the United States Pharmacopoeia by Nexera™ XR - High Performance Liquid Chromatography [ PDF / 75.14KB ]

Ultra Fast Method Scouting - - Maximizing Efficiency for Method Development - [ PDF / 703.03KB ]

LCMS Bioanalysis of Antibody Drugs Using Fab-selective Proteolysis "nSMOL Method" - -Selection of Signature Peptide - [ PDF / 412.89KB ]

USP method transfer on UHPLC is no more challenge for the analysis of Amoxicillin Oral Suspension - Nexera UHPLC [ PDF / 352.76KB ]

Development of a Spectrum Library of Endocrine Disruptors by LCMS-IT-TOF [ PDF / 1.14MB ]

Incorporating Analytical Intelligence into the Integrated i-Series—New Analytical Workflow Automation [ PDF / 419.68KB ]

Determination of Alcohol in Hand Sanitizer by Headspace GC-FID [ PDF / 211.06KB ]

System Suitability Test of Low-Substituted Hydroxypropyl Cellulose for USP42-NF37 - Gas Chromatography [ PDF / 71.98KB ]

Analysis of THC and CBD Content in Hemp Oil Using GC-FID and Hydrogen Carrier Gas [ PDF / 573.11KB ]

X-Ray Fluorescence Analysis of Light Elements in Liquid Samples – EDX-8100 and Helium Purge Unit – - X-Ray Analysis [ PDF / 488.65KB ]

X-Ray Fluorescence Analysis of Tablets - X-Ray Analysis [ PDF / 564.05KB ]

ICH Q3D Elemental Impurities Analysis of Drug Substances by EDX - X-Ray Analysis [ PDF / 173.45KB ]

Analysis of Food Contaminants by EDX and FTIR - Dental Materials - - X-Ray Analysis [ PDF / 618.52KB ]

A Goal-Oriented Approach to the Quantitative Determination of Cannabinoids by HPLC - Pittcon 2017 1130-12 [ PDF / 434.07KB ]

Monoclonal Antibody Workflows on the Shimadzu Q-TOF LCMS-9030 Using the Protein Metrics Software Suite - Liquid Chromatography Mass Spectrometry [ PDF / 1.49MB ]

Mice fecal metabolomics by LC-MS/MS: Comparison between young mice and old mice - ASMS 2017 MP 455 [ PDF / 799.55KB ]

Quantitative Analysis of Steroid Hormones Using Triple Quadrupole LC/MS/MS - Liquid Chromatography Mass Spectrometry [ PDF / 1.30MB ]

Bioanalytical Method for Quantification of Polymyxin B1, B2, B3 and Isoleucine-polymyxin B1 in Human Plasma [ PDF / 451.88KB ]

Improvement of Quantitative Performance for Ibuprofen Using UV Cut-Off Filter on SPD-M40 - High Performance Liquid Chromatography [ PDF / 296.75KB ]

Validation of Analysis Method Using ICPMS-2030 Based on USP ELEMENTAL IMPURITIES - PROCEDURES - Inductively Coupled Plasma Mass Spectrometry [ PDF / 143.31KB ]

Detection of Circular Plasmid DNA by MultiNA™ [ PDF / 251.77KB ]

Micro-Volume DNA Quantitation Using TrayCell - Spectrophotometric Analysis [ PDF / 961.99KB ]

Quantitation of DNA Using Nano Stick - Spectrophotometric Analysis [ PDF / 1.14MB ]

Introduction of Performance Validation Software for Improved GLP/GMP Support - Spectrophotometric Analysis [ PDF / 1.46MB ]

Characterization of Insoluble Subvisible Particles in Biopharmaceuticals by Flow Imaging Method - Powder Property Analysis [ PDF / 1.43MB ]

Orthodontic Implant Fatigue Testing - Material Testing System [ PDF / 309.66KB ]

Tensile Testing of Cultured Epidermis - Material Testing System [ PDF / 322.44KB ]

Evaluation of Amyloid-β Aggregation by RF-6000 Spectrofluorophotometer - Spectrophotometric Analysis [ PDF / 94.87KB ]

Quick Screening and Quantitative Analysis of Carcinogens in Medicinal Plants Using DPiMS™-8060 - Probe Electrospray Ionization Method [ PDF / 343.40KB ]

Quantitative Analysis of Oxytocin in Rat Plasma Using LC/MS/MS - Liquid Chromatograph-Mass Spectrometry [ PDF / 71.29KB ]

Evaluation of Undifferentiated State of Human iPS Cells Using C2MAP™ Cell Culture Media Analysis Platform - Liquid Chromatograph-Mass Spectrometry [ PDF / 1.76MB ]

LCMS-8045 Application Booklet - Liquid Chromatograph-Mass Spectrometry [ PDF / 12.37MB ]

Development of a Spectrum Library of Endocrine Disruptors by LCMS-IT-TOF [ PDF / 1.14MB ]

Comparison of Separation and Selectivity of Nexera™ Organic Acid Analysis System and Reversed Phase-UV Method [ PDF / 114.35KB ]

Analysis of Methanol in Ethanol-based Sanitizer [ PDF / 118.94KB ]

Measurement of Purine Content in Foods Using HPLC - High Performance Liquid Chromatography [ PDF / 145.32KB ]

Quantification of Nicotine in E-cigarette Liquid Sample Using GC-FID and Hydrogen Carrier Gas [ PDF / 433.50KB ]

Impurity Analysis in Pharmaceutical Products with the Advanced Photodiode Array Detector SPD-M40 - High Performance Liquid Chromatography [ PDF / 209.03KB ]

Quantitative clinical toxicological screening comparing Library ID from production scan MS/MS to MRM Spectrum mode ID [ PDF / 309.20KB ]

Development and Validation of LC/MS/MS Method with Ultra Small-Volume Injection for Quantitative Determination of Alprazolam in Human Plasma [ PDF / 109.04KB ]

Development and Validation of Liquid Chromatography-Time of Flight Method of Bacopaside-I and Metabolites for Pharmacokinetic Study [ PDF / 216.50KB ]

Fragmentation Outcome Modelling: Prototype software for prediction of CID fragment ions for small molecule structures [ PDF / 1.73MB ]

Measurement of Heavy Metals (Cd, Pb) in Pet Food by AAS [ PDF / 187.16KB ]

Measurement of Metal Ion in Plating Solution by Flame Atomic Absorption [ PDF / 1.08MB ]

Na Analysis by Atomic Absorption [ PDF / 185.95KB ]

Residual Solvents Analysis in Pharmaceutical Products (Part 7) - Thermostatting Dependencies of Aqueous Solution /Water Dilution Effect on DMSO Solution [ PDF / 70.09KB ]

Screening of 25-OH Vitamin D2,D3 using Shimadzu LCMS-8040 [ PDF / 358.44KB ]

Sensitive detection and quantification of hydrogen sulfide as a gasotransmitter by combining monobromobimane-based derivatization to triple quadrupole LC/MS/MS [ PDF / 245.30KB ]

Shimadzu Posters at ASMS 2015 [ ZIP / 35.34MB ]

The Determination of Hazardous Substances According to RoHS and WEEE Directives [ PDF / 197.24KB ]

Using the LCMS IT TOF to identify impurities in pharmaceutical candidates using high mass accuracy [ PDF / 260.20KB ]

Analysis of Pharmaceuticals’ Impurity - Regulations and Analysis for Carcinogenic Substances - [ PDF / 705.37KB ]

Fully automated platform for TDM analysis in serum samples [ PDF / 1.02MB ]

UV TALK LETTER Vol. 17 [ PDF / 1.25MB ]

Analysis of Food for Contamination [ PDF / 60.93KB ]

UV TALK LETTER Vol. 19 [ PDF / 5.38MB ]

High-Speed Analysis of Linezolid following the Draft Guidance of International Harmonization of Pharmacopoeias - High Performance Liquid Chromatography [ PDF / 115.15KB ]

Alcohol Determination of Sanitizer Gel in accordance with USP - Gas Chromatography [ PDF / 106.81KB ]

Vol.3, Issue3-Dec 2015 Pharmaceutical Analysis [ PDF / 2.36MB ]

Vol.2, Issue1-January 2014 Pharmaceuticals and Hum [ PDF / 3.13MB ]

Shimadzu Journal Vol.8 Issue1-July 2020 Pharmaceutical [ PDF / 14.51MB ]

Solutions for Pharmaceutical Impurities [ PDF / 7.02MB ]

Solutions for Biopharmaceutical [ PDF / 16.14MB ]

Improvement of Quantitative Performance for Ibuprofen Using UV Cut-Off Filter on SPD-M40 - High Performance Liquid Chromatography [ PDF / 296.75KB ]

Analysis of Purified Glucose and Glucose Hydrate in Accordance with the Japanese Pharmacopoeia - High Performance Liquid Chromatography [ PDF / 86.73KB ]

Fast Quantitative Analysis of Aminoglycoside Antibiotic Residues in Meat, Eggs and Milk and Identity Confirmation with MRM Spectrum Mode - LC/MS [ PDF / 854.29KB ]

Analysis of Short-Chain Fatty Acids/Organic Acids (3-NPH Derivatives) in Fecal Specimens from SPF and Antibiotic-Fed Mice - Liquid Chromatograph Mass Spectrometry [ PDF / 61.77KB ]

Pharmaceutical Analysis [ PDF / 14.51MB ]

High-Sensitivity Analysis of Drugs in Ultra-Small Volumes Plasma Samples Using Micro-Flow LC-MS/MS [ PDF / 871.42KB ]

Analysis of Pharmaceutical Products [ PDF / 109.77KB ]

Analysis of 3-MCPD Fatty Acid Diesters in Palm Oil Using a Triple Quadrupole LC/MS/MS [LCMS-8030] [ PDF / 974.20KB ]

Next Industry Standard Nexis GC-2030 with HS-20 made drug substance residual solvent analysis simpler with constant flow mode - Nexis GC‐2030 with HS‐20 [ PDF / 204.08KB ]

Packed Column Analysis of Alcohol Number Determination Conforming to Japanese Pharmacopoeia Using Nexis™ GC-2030 (FID) [ PDF / 343.35KB ]

Evaluation of Membrane Protein Properties by Fluorescence-Detection Size-Exclusion Chromatography (FSEC) Using an HPLC System [ PDF / 1.79MB ]

Supercritical Fluid Extraction/Chromatography - Applications Handbook [ PDF / 14.29MB ]

Analysis of Hydrogen Bond by Near Infrared Spectrometry - SPECTROPHOTOMETRIC ANALYSIS [ PDF / 144.39KB ]

ICH Q3D Elemental Impurities Analysis of Tablets by EDX - Verification Based on USP ELEMENTAL IMPURITIES-PROCEDURES - - X-Ray Analysis [ PDF / 222.86KB ]

Basics & Fundamentals: Gas Chromatography [ PDF / 1.13MB ]

Verification of Quantitativity and Confirmation of Molecular Weight of Oligonucleotide therapeutics Using LCMS™-8060 - Liquid Chromatography Mass Spectrometry [ PDF / 222.79KB ]

LCMS™ Bioanalysis of Antibody Drugs Using Fab- Selective Proteolysis nSMOL - Part 7 - Tocilizumab Analysis - - nSMOL Antibody BA Kit [ PDF / 444.63KB ]

TOC Measurement Using Pre-Cleaned Vials [ PDF / 307.37KB ]

Determination of Ethanol Content in and Simple Fail/Pass Judgment of Alcohol Hand Sanitizer by FTIR - Fourier Transform Infrared Spectrophotometer (FTIR) [ PDF / 1.28MB ]

JP- and EP-Compliant Analysis of Impurities of COVID-19 Drug Dexamethasone [ PDF / 94.62KB ]

Simultaneous Analysis of Benzotriazole, Tolutriazole Derivatives and Furanic Compounds: Passivators in Insulating Oil [ PDF / 332.00KB ]

Nexera MX [ PDF / 5.95MB ]

TOC System Suitability Test Using TOC-1000e According to USP 643 [ PDF / 513.60KB ]

Online Measurement of Ultra-pure Water Using TOC-1000e [ PDF / 571.13KB ]

High-Sensitivity Analysis of Drugs in Ultra-Small Volume Plasma Samples Using Microflow LC/MS/MS [ PDF / 245.35KB ]

A Fast LC/MS/MS method for Determination of Telmisartan in Human Plasma by LC-MS-MS [ PDF / 232.07KB ]

Analysis of 10 kinds of Maltooligosaccharides in a Soft Drink by ELSD-LT III [ PDF / 139.14KB ]

ELSD-LT III [ PDF / 2.73MB ]

Quantitative Analysis of Favipiravir Spiked in Plasma Using by HPLC - High Performance Liquid Chromatography [ PDF / 225.93KB ]

Optimizing Aggregates Analysis – Mobile Phase [ PDF / 556.56KB ]

Exploring Factors That Influence Charge Variant Analysis of mAbs with Shim-pack Bio IEX Columns using Salt Gradient Elution [ PDF / 429.11KB ]

Analysis of Residual Solvents in Pharmaceutical Products by Headspace-GC-FID with Nitrogen Carrier Gas Following USP- Procedure B [ PDF / 322.07KB ]

Analysis of Sodium Chondroitin Sulfate by ELSD-LT III [ PDF / 131.97KB ]

High Speed Analysis of Monosaccharides and Disaccharides in Soft Drinks by ELSD-LT III [ PDF / 141.62KB ]

A new method for the analysis of increased D-amino acids in proteins due to aging [ PDF / 10.62MB ]

Optimizing Aggregate Analysis – Pore Size [ PDF / 368.82KB ]

High Sensitivity Analysis of Testosterone in Human Serum Using LCMS™-8060NX [ PDF / 1.03MB ]

High Sensitivity Analysis of Aldosterone in Human Serum Using LCMS™-8060NX [ PDF / 1.02MB ]

Analysis of Favipiravir in Human Plasma [ PDF / 407.40KB ]

Analysis of Favipiravir in Human Plasma Using Fully Automated Sample Preparation LC/MS/MS System [ PDF / 908.44KB ]

Profiling of Bile Acids in Human Plasma Using Triple Quadrupole Mass Spectrometer [ PDF / 821.99KB ]

Simple Method Transfer using i-Series (LC-2050/LC-2060) [ PDF / 321.29KB ]